Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | XBP1 | P17861 | 2/20 | 0.39 |
| ▸ | MPI | P34949 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970830 | 0.78 | HSP90AA1 (0.35) | MAPTLMNANPSR1PKMALDH1A1 | |
| SCHEMBL180646 | 0.75 | LMNA (0.36) | MAPTLMNAALDH1A1MAPK1PABPC1 | |
| SCHEMBL13525191 | 0.74 | HSD17B10 (0.35) | MAPTLMNAHTTNPSR1PKM | |
| SCHEMBL599195 | 0.74 | LMNA (0.35) | MAPTLMNAALDH1A1MAPK1PABPC1 | |
| SCHEMBL8850269 | 0.72 | MAPT (0.45) | MAPTLMNAHTTPKMALDH1A1 | |
| SCHEMBL11787610 | 0.71 | PABPC1 (0.41) | MAPTLMNAHTTNPSR1PKM | |
| SCHEMBL8148882 | 0.71 | GLB1 (0.35) | MAPTLMNAALDH1A1MAPK1HPGD | |
| SCHEMBL11422063 | 0.70 | MAPT (0.42) | MAPTLMNAHTTNPSR1PKM | |
| SCHEMBL6949065 | 0.68 | LMNA (0.39) | MAPTLMNANPSR1ALDH1A1MAPK1 | |
| SCHEMBL11410974 | 0.68 | PABPC1 (0.39) | MAPTNPSR1PKMALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3928070-B2 | — | — | 2007-06-13 | — | — | JP | claimed |
| EP-0767809-A2 | CURE-INDICATING MOLDING AND COATING COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-04-16 | — | — | EP | claimed |
| WO-1996000745-A2 | CURE-INDICATING MOLDING AND COATING COMPOSITION | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-11 | — | — | WO | claimed |
| US-3981676-A | HAIR DYES | L'OREAL (FR) | 1976-09-21 | — | — | US | claimed |
| US-3989447-A | Process for nonpermanently dyeing human hair with indamine indoaniline and indophenol hair dyes | SOCIETE ANONYME DITE: L'OREAL (FR) | 1976-11-02 | — | — | US | disclosed |
| US-3981676-A | HAIR DYES | L'OREAL (FR) | 1976-09-21 | — | — | US | disclosed |