Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5517320 | 0.81 | GABRR1 (0.36) | PTGDR2KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5521343 | 0.79 | GCK (0.36) | PTGDR2POLBALDH1A1AKR1B1MAPT | |
| SCHEMBL5518909 | 0.79 | PKM (0.34) | PTGDR2KDM4EPOLBALDH1A1AKR1B1 | |
| SCHEMBL26924096 | 0.78 | — | — | |
| SCHEMBL14215510 | 0.77 | PTGDR2 (0.43) | PTGDR2KDM4EPOLBALDH1A1MAPT | |
| SCHEMBL5514684 | 0.76 | KDM4E (0.49) | PTGDR2KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL5513251 | 0.76 | AKR1B1 (0.32) | AKR1B1 | |
| SCHEMBL11564617 | 0.73 | CYP1A2 (0.46) | PTGDR2KDM4EPOLBALDH1A1AKR1B1 | |
| SCHEMBL4093001 | 0.71 | GABRR1 (0.39) | PTGDR2KDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL5516134 | 0.70 | PTGDR2 (0.40) | PTGDR2KDM4EPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8367666-B2 | 3-carbamoyl-2-pyridone derivatives | SHIONOGI & CO., LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |
| US-8178681-B2 | methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency | SHIONOGI & CO., LTD. (JP) | 2012-05-15 | — | — | US | disclosed |