SCHEMBL5517488

SCHEMBL5517488

CNc1ccc(N)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.38
ALDH1A1 P00352 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522910 0.85 PRKCI (0.35) PRKCIIDO1
SCHEMBL5513043 0.84 IDO1 (0.37) PRKCIALDH1A1IDO1
SCHEMBL5506968 0.79 CYP3A4 (0.39) PRKCIALDH1A1
SCHEMBL20076621 0.76 PRKCI (0.34) PRKCIALDH1A1IDO1
SCHEMBL5522370 0.76 PRKCI (0.34) PRKCI
SCHEMBL20226651 0.76 KDM4E (0.43) ALDH1A1IDO1
SCHEMBL20149267 0.76 IDO1 (0.36) IDO1
SCHEMBL5513611 0.76 ALDH1A1 (0.45) ALDH1A1
SCHEMBL7995306 0.75 ALDH1A1 (0.41) ALDH1A1
SCHEMBL5509898 0.74 PRKCI (0.35) PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed