Dimethylamine

Dimethylamine

SCHEMBL5517540

CNC.Clc1ccc(C=Cc2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.52
NFE2L2 Q16236 2/20 0.52
EGFR P00533 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MAOB P27338 2/20 0.48
CYP1B1 Q16678 1/20 0.48
RELA Q04206 1/20 0.48
TRPA1 O75762 1/20 0.48
CYP19A1 P11511 1/20 0.48
MAOA P21397 1/20 0.48
ALOX5 P09917 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699518 0.91 AHR (0.61) AHRNFE2L2EGFRMMP1MMP2
SCHEMBL18416526 0.91 AHR (0.61) AHRNFE2L2EGFRMMP1MMP2
SCHEMBL14947044 0.91 AHR (0.61) AHRNFE2L2EGFRMMP1MMP2
SCHEMBL699519 0.91 AHR (0.61) AHRNFE2L2EGFRMMP1MMP2
(Z)-1,2-Diphenylethene SCHEMBL5492329 0.85 MAOB (0.58) NFE2L2MAOBRELATRPA1CYP19A1
SCHEMBL18416524 0.84 MAOB (0.67) AHRNFE2L2EGFRMMP1MMP2
SCHEMBL9971887 0.84 CYP1A2 (0.64) AHRNFE2L2EGFRMMP1MMP2
(Z)-1,2-Diphenylethene SCHEMBL28535457 0.83 TSHR (0.65) AHRNFE2L2EGFRMMP1MMP2
Diphenylamine SCHEMBL10827517 0.83 MAPT (0.52) AHRNFE2L2EGFRMMP1MMP2
SCHEMBL137664 0.81 MAOB (0.70) AHRNFE2L2EGFRMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262252-B2 Nonlinear optical materials comprising fluorine-containing polymer DAIKIN INDUSTRIES, LTD. (JP) 2007-08-28 US disclosed
US-20060189788-A1 Cyclic ether copolymer, coating resin composition, optical devices, and process for production of the devices DAIKIN INDUSTRIES, LTD. (JP) 2006-08-24 US disclosed
US-20050004253-A1 Nonlinear optical materials comprising fluorine-containing polymer DAIKIN INDUSTRIES, LTD 2005-01-06 US disclosed
EP-1406116-A1 NONLINEAR OPTICAL MATERIAL CONTAINING FLUOROPOLYMER Daikin Industries, Ltd. (JP) 2004-04-07 EP disclosed