Sugi Predict

Sugi Predict / Compounds / SCHEMBL699518

SCHEMBL699518

SCHEMBL699518

Clc1ccc(/C=C/c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AHR P35869 1/20 0.61
▸ NFE2L2 Q16236 2/20 0.59
▸ MAOB P27338 3/20 0.56
▸ CYP19A1 P11511 1/20 0.56
▸ MAOA P21397 1/20 0.56
▸ CYP1B1 Q16678 1/20 0.55
▸ TSHR P16473 1/20 0.53
▸ RELA Q04206 2/20 0.50
▸ CYP1A2 P05177 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ TRPA1 O75762 1/20 0.50
▸ PPARG P37231 1/20 0.50
▸ EGFR P00533 1/20 0.50
▸ MMP1 P03956 1/20 0.50
▸ MMP2 P08253 1/20 0.50
▸ MMP9 P14780 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ NPC1 O15118 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL699519 1.00 AHR (0.61) AHRNFE2L2MAOBCYP19A1MAOA
SCHEMBL18416526 1.00 AHR (0.61) AHRNFE2L2MAOBCYP19A1MAOA
SCHEMBL14947044 1.00 AHR (0.61) AHRNFE2L2MAOBCYP19A1MAOA
SCHEMBL9971887 0.93 CYP1A2 (0.64) AHRNFE2L2MAOBCYP19A1MAOA
SCHEMBL18416524 0.93 MAOB (0.67) AHRNFE2L2MAOBCYP19A1MAOA
(Z)-1,2-Diphenylethene SCHEMBL28535457 0.92 TSHR (0.65) AHRNFE2L2MAOBCYP19A1MAOA
Dimethylamine SCHEMBL5517540 0.91 AHR (0.52) AHRNFE2L2MAOBCYP19A1MAOA
SCHEMBL2622613 0.90 MAOB (0.70) AHRNFE2L2MAOBMAOACYP1B1
SCHEMBL137664 0.90 MAOB (0.70) AHRNFE2L2MAOBMAOACYP1B1
SCHEMBL2622601 0.90 MAOB (0.70) AHRNFE2L2MAOBMAOACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404221-B2 Methods of arene alkenylation UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2025-09-02 — — US disclosed
CN-118843614-A High-purity 4- (2-bromoethyl) benzenesulfonic acid, high-purity styrenesulfonic acid derived therefrom, polymer thereof, and process for producing these 东曹精细化工株式会社 2024-10-25 — — CN disclosed
US-11858889-B2 Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease THE TRUSTEES OF INDIANA UNIVERSITY (US) 2024-01-02 — — US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 — — US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 — — US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 — — US disclosed
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 — — WO disclosed
CN-108658718-B Preparation method of trans-stilbene compound 温州大学 2020-12-18 — — CN disclosed
CN-111233610-A Synthesis method of trans-olefin compound 五邑大学 2020-06-05 — — CN disclosed
EP-3415495-A1 TRIPHENYLAMINE DERIVATIVE, CHARGE TRANSPORT MATERIAL PRODUCED USING SAME, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR Takasago International Corporation (JP) 2018-12-19 — — EP disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 — — US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 — — US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 — — US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 — — US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 — — US disclosed
US-4420435-A Alpha-hydroxy-phosphonic acid esters BAYER AKTIENGESELLSCHAFT (DE) 1983-12-13 — — US disclosed
EP-0041043-B1 PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE CIBA-GEIGY AG (CH) 1983-11-09 — — EP disclosed
US-4358409-A Preparation of styryl cyclopropane insecticide intermediates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-09 — — US disclosed
US-4335055-A Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 — — US disclosed
EP-0041043-A1 Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene CIBA-GEIGY AG (CH) 1981-12-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR AHR 3/4885NFE2L2 102/4885MAOB 157/4885
US-12404221-B2 Methods of arene alkenylation CYBB, CBR3, AHR AHR 3/4885NFE2L2 102/4885MAOB 157/4885
US-11858889-B2 Compound for modulating DDAH and ADMA levels, as well as methods of using thereof to treat disease ADM2, DDAH1, BHMT AHR 636/4885NFE2L2 713/4885MAOB 544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.