Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.58 |
| ▸ | CHAT | P28329 | 2/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | RELA | Q04206 | 2/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (Z)-1,2-Diphenylethene SCHEMBL28291545 | 0.87 | MAOB (0.65) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL347707 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL21847984 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL9488275 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL9134296 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL9134305 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL443 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL22712863 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL9488270 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL442 | 0.87 | MAOB (0.73) | MAOBCHATNFE2L2CYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980954-B2 | Substituted cis- and trans-stilbenes as therapeutic agents | STC.UNM (US) | 2015-03-17 | — | — | US | claimed |
| CN-110015962-B | Stilbene analogs and methods of treating cancer | 肯塔基大学研究基金会 | 2022-03-15 | — | — | CN | disclosed |
| US-9925153-B2 | Therapeutic agents for skin diseases and conditions | STC.UNM (US) | 2018-03-27 | — | — | US | disclosed |
| EP-2673250-B1 | STILBENE ANALOGS AND METHODS OF TREATING CANCER | UNIV KENTUCKY RES FOUND (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM | 2016-10-06 | — | — | US | disclosed |
| US-9132102-B2 | Stilbene analogs and methods of treating cancer | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2015-09-15 | — | — | US | disclosed |
| WO-2015085143-A2 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | STC.UNM (US) | 2015-06-11 | — | — | WO | disclosed |
| US-8980954-B2 | Substituted cis- and trans-stilbenes as therapeutic agents | STC.UNM (US) | 2015-03-17 | — | — | US | disclosed |
| US-20150037253-A1 | METAL COMPLEXES AS IMAGING AGENTS | THE UNIVERSITY OF MELBOURNE (AU) | 2015-02-05 | — | — | US | disclosed |
| US-20140249161-A1 | STILBENE ANALOGS AND METHODS OF TREATING CANCER | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-09-04 | — | — | US | disclosed |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2007-10-25 | — | — | US | disclosed |
| US-7262252-B2 | Nonlinear optical materials comprising fluorine-containing polymer | DAIKIN INDUSTRIES, LTD. (JP) | 2007-08-28 | — | — | US | disclosed |
| US-20060189788-A1 | Cyclic ether copolymer, coating resin composition, optical devices, and process for production of the devices | DAIKIN INDUSTRIES, LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20050004253-A1 | Nonlinear optical materials comprising fluorine-containing polymer | DAIKIN INDUSTRIES, LTD | 2005-01-06 | — | — | US | disclosed |
| EP-1406116-A1 | NONLINEAR OPTICAL MATERIAL CONTAINING FLUOROPOLYMER | Daikin Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6392111-B1 | REACTING AROMATIC COMPOUND WITH OLEFIN | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2002-05-21 | — | — | US | disclosed |
| US-5198318-A | Bisazo photoconductor for electrophotography | FUJI ELECTRIC CO., LTD. (JP) | 1993-03-30 | — | — | US | disclosed |
| US-4618559-A | Process of making electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 1986-10-21 | — | — | US | disclosed |
| US-4421838-A | REDUCTION OF SELENIUM COMPOUND IN DIELECTRIC POLYMER | FUJI PHOTO FILM CO., LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4349617-A | Function separated type electrophotographic light-sensitive members and process for production thereof | FUJI PHOTO FILM CO., LTD. (JP) | 1982-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160287531-A1 | THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS | CUTA, TSLP, ELANE | MAOB 961/4885CHAT 2682/4885NFE2L2 696/4885 |
| US-20150037253-A1 | METAL COMPLEXES AS IMAGING AGENTS | APBA1, TBCB, PSEN1 | MAOB 441/4885CHAT 1546/4885NFE2L2 391/4885 |
| US-20140249161-A1 | STILBENE ANALOGS AND METHODS OF TREATING CANCER | BRCA1, APC, MSH2 | MAOB 786/4885CHAT 4064/4885NFE2L2 265/4885 |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | TGFB1, VHL, TMSB10 | MAOB 1359/4885CHAT 673/4885NFE2L2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.