SCHEMBL5517833

SCHEMBL5517833

COCOc1ccc(Cc2cc3ccccc3s2)cc1C1(O)O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 6/20 0.38
TACR2 P21452 1/20 0.31
SSTR4 P31391 2/20 0.31
PTPN1 P18031 1/20 0.31
SSTR1 P30872 1/20 0.31
SSTR2 P30874 1/20 0.31
SSTR3 P32745 1/20 0.31
SSTR5 P35346 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1774436 0.83 SLC5A2 (0.34) SLC5A2TACR2SSTR4PTPN1
SCHEMBL12425872 0.80 SLC5A2 (0.48) SLC5A2TACR2SSTR4PTPN1SSTR1
SCHEMBL1774673 0.79 SLC5A2 (0.34) SLC5A2TACR2
SCHEMBL1775979 0.79 TACR2 (0.34) TACR2SSTR4SSTR1SSTR2SSTR3
SCHEMBL1775976 0.78 CLK1 (0.37) SLC5A2TACR2SSTR4PTPN1SSTR1
SCHEMBL5270077 0.78 TACR2 (0.35) SLC5A2TACR2PTPN1
SCHEMBL5270081 0.78 TACR2 (0.35) SLC5A2TACR2PTPN1
SCHEMBL20741941 0.77 SLC5A2 (0.37) SLC5A2
SCHEMBL20139462 0.77 PTPN1 (0.34) SLC5A2TACR2PTPN1
SCHEMBL1775301 0.76 TP53 (0.32) SLC5A2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070161787-A1 C-glycoside derivatives and salts thereof ASTELLAS PHARMA INC. (JP) 2007-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070161787-A1 C-glycoside derivatives and salts thereof SLC5A1, SLC5A2, SLC2A1 SLC5A2 2/4885TACR2 1041/4885SSTR4 1087/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.