SCHEMBL1774673

SCHEMBL1774673

COc1c(Cc2cc3ccccc3s2)cc(C2(O)O[C@H](COCc3ccccc3)[C@H](OCc3ccccc3)[C@@H](OCc3ccccc3)[C@H]2OCc2ccccc2)c2ccccc12

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 5/20 0.34
SLC5A1 P13866 3/20 0.32
TACR2 P21452 1/20 0.31
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1774436 0.86 SLC5A2 (0.34) SLC5A2TACR2CHRNA7
SCHEMBL1775976 0.82 CLK1 (0.37) SLC5A2TACR2
SCHEMBL1774693 0.81 SLC5A2 (0.38) SLC5A2SLC5A1TACR2
SCHEMBL1775979 0.80 TACR2 (0.34) TACR2
SCHEMBL5517833 0.79 SLC5A2 (0.38) SLC5A2TACR2
SCHEMBL20741941 0.79 SLC5A2 (0.37) SLC5A2SLC5A1
SCHEMBL1775301 0.79 TP53 (0.32) SLC5A2
SCHEMBL1776117 0.79 TP53 (0.32) SLC5A2
SCHEMBL1774735 0.78 SLC5A2 (0.33) SLC5A2SLC5A1
SCHEMBL12605356 0.76 TACR2 (0.37) TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7943748-B2 Glucitol derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-05-17 US disclosed
US-20080319047-A1 Novel Glucitol Derivative, Prodrug Thereof And Salt Thereof, And Therapeutic Agent Containing The Same For Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
EP-1803721-A1 NOVEL GLUCITOL DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319047-A1 Novel Glucitol Derivative, Prodrug Thereof And Salt Thereof, And Therapeutic Agent Containing The Same For Diabetes SLC5A1, SLC5A2, GPR119 SLC5A2 2/4885SLC5A1 1/4885TACR2 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.