Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HTR2C | P28335 | 6/20 | 0.60 |
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | HTR2B | P41595 | 3/20 | 0.58 |
| ▸ | HTR1D | P28221 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.58 |
| ▸ | HTR3B | O95264 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 1/20 | 0.58 |
| ▸ | HTR1E | P28566 | 1/20 | 0.58 |
| ▸ | HTR1F | P30939 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283499 | 0.85 | GAA (0.69) | GAAHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL5528244 | 0.84 | TRPV1 (0.64) | CYP2D6CYP3A4CYP1A2NPSR1MAPT | |
| SCHEMBL17525726 | 0.83 | GAA (0.66) | GAAHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL2531516 | 0.83 | GAA (1.00) | GAAHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL5520092 | 0.82 | TRPV1 (0.67) | CYP2D6CYP3A4CYP1A2NPSR1MAPT | |
| SCHEMBL10256766 | 0.80 | HTR2A (0.64) | HTR2CHTR1AHTR2AHTR7CYP2D6 | |
| SCHEMBL7002494 | 0.77 | HTR2C (0.77) | GAAHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL26508359 | 0.76 | HTR7 (0.71) | GAAHTR2CHTR1AHTR2AHTR7 | |
| SCHEMBL27095364 | 0.76 | HTR7 (0.71) | HTR2CHTR1AHTR2AHTR7CYP2D6 | |
| SCHEMBL233744 | 0.76 | HTR2C (1.00) | GAAHTR2CHTR1AHTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | claimed |
| US-7153977-B2 | Ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-12-26 | — | — | US | claimed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | claimed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | claimed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | claimed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | claimed |
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | disclosed |
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | disclosed |
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | disclosed |
| US-7153977-B2 | Ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-12-26 | — | — | US | disclosed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | disclosed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | disclosed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | disclosed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051348-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | GAA 1918/4885HTR2C 1349/4885HTR1A 956/4885 |
| US-20070027310-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | GAA 1918/4885HTR2C 1349/4885HTR1A 956/4885 |
| US-20040132981-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | GAA 1918/4885HTR2C 1349/4885HTR1A 956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.