Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.64 |
| ▸ | SPR | P35270 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520092 | 0.94 | TRPV1 (0.67) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL25137286 | 0.85 | TRPV1 (0.76) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5517866 | 0.84 | GAA (0.70) | SPRKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4686124 | 0.83 | TRPV1 (0.84) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| Bufobutanoic Acid SCHEMBL22804772 | 0.82 | TRPV1 (0.71) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| Bufobutanoic Acid SCHEMBL29679385 | 0.82 | TRPV1 (0.71) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| N-Dihydro-P-Coumaroylserotonin SCHEMBL10070986 | 0.81 | TRPV1 (0.72) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL2271234 | 0.80 | SPR (0.74) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL15232329 | 0.80 | TRPV1 (0.76) | TRPV1SPRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL31036202 | 0.80 | TRPV1 (0.91) | TRPV1SPRKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | claimed |
| US-7153977-B2 | Ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-12-26 | — | — | US | claimed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | claimed |
| CN-1418111-A | Novel Ligands and method for preparing same | NAT UNIV SINGAPORE (SG) | 2003-05-14 | — | — | CN | claimed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | claimed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | claimed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | claimed |
| US-20070027310-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2007-02-01 | — | — | US | disclosed |
| US-7153977-B2 | Ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2006-12-26 | — | — | US | disclosed |
| US-20040132981-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-07-08 | — | — | US | disclosed |
| CN-1418111-A | Novel Ligands and method for preparing same | NAT UNIV SINGAPORE (SG) | 2003-05-14 | — | — | CN | disclosed |
| EP-1289561-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-03-12 | — | — | EP | disclosed |
| US-20010051348-A1 | Novel ligands and methods for preparing same | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-12-13 | — | — | US | disclosed |
| WO-2001054731-A2 | LIGAND CONJUGATES AND METHODS FOR PREPARING SAME | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010051348-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | TRPV1 847/4885SPR 135/4885KDM4E 4747/4885 |
| US-20070027310-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | TRPV1 847/4885SPR 135/4885KDM4E 4747/4885 |
| US-20040132981-A1 | Novel ligands and methods for preparing same | ADGRF1, ADGRE5, TACR2 | TRPV1 847/4885SPR 135/4885KDM4E 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.