SCHEMBL5518010

SCHEMBL5518010

Oc1cc(F)c(F)c2c(O)cccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.52
ALOX15 P16050 2/20 0.52
RECQL P46063 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MAPT P10636 2/20 0.52
APP P05067 1/20 0.52
THRB P10828 1/20 0.52
TSHR P16473 1/20 0.52
CASP1 P29466 1/20 0.52
SNCA P37840 1/20 0.52
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
DNMT1 P26358 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
KMT2A Q03164 1/20 0.39
MCL1 Q07820 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
IMPDH2 P12268 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5522970 0.82 TSHR (0.38) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL5511582 0.78 IDO1 (0.41) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL5507591 0.76 KDM4E (0.33) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL7721773 0.76 HPGD (0.52) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL31037128 0.76 HPGD (0.58) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL4635862 0.76 HPGD (0.58) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL5522395 0.74 HPGD (0.70) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL25422200 0.72 HPGD (0.54) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL5510267 0.72 HPGD (0.54) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL25421290 0.72 HPGD (0.48) HPGDALOX15RECQLHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208559-B2 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2007-04-24 US disclosed
US-20060135712-A1 Ethylened polymer and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2006-06-22 US disclosed