SCHEMBL4635862

SCHEMBL4635862

Oc1cc(O)c2cccc(O)c2c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.58
ALOX15 P16050 3/20 0.58
RECQL P46063 3/20 0.58
HSD17B10 Q99714 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
THRB P10828 3/20 0.58
MAPT P10636 2/20 0.58
SNCA P37840 2/20 0.58
APP P05067 1/20 0.58
TSHR P16473 1/20 0.58
CASP1 P29466 1/20 0.58
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
DNMT1 P26358 1/20 0.48
CACNA1B Q00975 1/20 0.48
APBA1 Q02410 1/20 0.48
MCL1 Q07820 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
CDK2 P24941 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31037128 1.00 HPGD (0.58) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL18068458 0.84 HPGD (0.56) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL13300910 0.83 MAPT (0.56) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL3220975 0.81 HPGD (0.58) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL7301115 0.80 HPGD (0.46) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL18716074 0.79 HPGD (0.62) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL7302249 0.77 MAPT (0.54) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL31256488 0.77 HPGD (0.59) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL18716135 0.77 HPGD (0.59) HPGDALOX15RECQLHSD17B10TDP1
SCHEMBL5518010 0.76 HPGD (0.52) HPGDALOX15RECQLHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190337966-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR OSAKA UNIVERSITY (JP) 2019-11-07 US disclosed
EP-3564245-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR Osaka University (JP) 2019-11-06 EP disclosed
WO-2018123207-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR 国立大学法人大阪大学 2018-07-05 WO disclosed
EP-1454919-B2 SCALE DEPOSIT INHIBITOR, PROCESS FOR ITS PRODUCTION, POLYMERIZER WHOSE INSIDE WALL IS COVERED WITH THE INHIBITOR, AND PROCESS FOR PRODUCTION OF VINYLIC POLYMERS BY THE USE OF THE POLYMERIZER TOKUYAMA CORP (JP) 2012-10-31 EP disclosed
EP-1454919-B1 SCALE DEPOSIT INHIBITOR, PROCESS FOR ITS PRODUCTION, POLYMERIZER WHOSE INSIDE WALL IS COVERED WITH THE INHIBITOR, AND PROCESS FOR PRODUCTION OF VINYLIC POLYMERS BY THE USE OF THE POLYMERIZER TOKUYAMA CORP (JP) 2008-06-18 EP disclosed
US-6894125-B2 Scale deposit inhibitor, process for its production, polymerizer whose inside wall is covered with the inhibitor, and process for production of vinylic polymers by the use of the polymerizer TOKUYAMA CORPORATION (JP) 2005-05-17 US disclosed
EP-1454919-A1 SCALE DEPOSIT INHIBITOR, PROCESS FOR ITS PRODUCTION, POLYMERIZER WHOSE INSIDE WALL IS COVERED WITH THE INHIBITOR, AND PROCESS FOR PRODUCTION OF VINYLIC POLYMERS BY THE USE OF THE POLYMERIZER Tokuyama Corporation (JP) 2004-09-08 EP disclosed
US-20040077804-A1 Scale deposit inhibitor, process for its production, polymerizer whose inside wall is covered with the inhibitor, and process for production of vinylic polymers by the use of the polymerizer TOKUYAMA CORPORATION (JP) 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337966-A1 NAPHTHOBISCHALCOGENADIAZOLE DERIVATIVE AND PRODUCTION METHOD THEREFOR CYP24A1, CYP26B1, CYP21A2 HPGD 815/4885ALOX15 2174/4885RECQL 2140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.