Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510267 | 0.86 | HPGD (0.54) | HPGDHSD17B10MAPTALOX15RECQL | |
| SCHEMBL25421290 | 0.82 | HPGD (0.48) | HPGDHSD17B10MAPTALOX15RECQL | |
| SCHEMBL25422200 | 0.77 | HPGD (0.54) | HPGDHSD17B10MAPTALOX15RECQL | |
| SCHEMBL5518010 | 0.76 | HPGD (0.52) | HPGDHSD17B10MAPTALOX15RECQL | |
| SCHEMBL7720985 | 0.75 | CRHBP (0.38) | HPGDHSD17B10MAPTTSHRCASP1 | |
| Boric Acid SCHEMBL28912173 | 0.73 | CES2 (0.34) | CYP1A2MEN1KMT2ACYP3A4RAB9A | |
| SCHEMBL19153758 | 0.71 | CYP1A2 (0.48) | HPGDHSD17B10MAPTTDP1TSHR | |
| SCHEMBL7716693 | 0.71 | ESR1 (0.33) | HPGDHSD17B10MAPTALOX15RECQL | |
| SCHEMBL27478351 | 0.71 | ALDH1A1 (0.48) | HPGDHSD17B10MAPTALOX15RECQL | |
| SCHEMBL31711763 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261573-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 Ontario Limited (CA) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001007386-A2 | ASYMMETRIC LIGANDS HAVING USE AS CATALYSTS | 1428388 ONTARIO LIMITED (CA) | 2001-02-01 | — | — | WO | disclosed |