⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL478015 | 0.73 | — | — | |
| SCHEMBL2904952 | 0.67 | — | — | |
| SCHEMBL828360 | 0.63 | — | — | |
| SCHEMBL6294988 | 0.61 | — | — | |
| SCHEMBL25392185 | 0.61 | — | — | |
| SCHEMBL287338 | 0.61 | — | — | |
| SCHEMBL38118 | 0.60 | — | — | |
| SCHEMBL17556551 | 0.59 | — | — | |
| SCHEMBL478011 | 0.59 | — | — | |
| SCHEMBL1148743 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070049600-A1 | PTERIDINONES AS KINASE INHIBITORS | WARNER-LAMBERT COMPANY | 2007-03-01 | — | — | US | disclosed |
| US-7169778-B2 | Pteridinones as kinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-7053070-B2 | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| US-6951946-B2 | Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates | LEXICON PHARMACEUTICALS, INC. (US) | 2005-10-04 | — | — | US | disclosed |
| EP-1173408-B1 | PPAR-(GAMMA) AGONISTS AS AGENTS FOR THE TREATMENT OF TYPE II DIABETES | COELACANTH CORP (US) | 2005-07-20 | — | — | EP | disclosed |
| US-20050154211-A1 | Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates | KOLB HARTMUTH C (US) | 2005-07-14 | — | — | US | disclosed |
| US-6891068-B2 | Water as promoter in the nucleophilic substitution of chloride | LEXICON PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |
| US-6806380-B2 | SUCH AS 1-METHOXY-2-(3-METHYLPHENYL)ETHANIMINE BY TREATING NITRILE WITH ANHYDROUS HYDROGEN CHLORIDE SOLUTION AND ANHYDROUS ALCOHOL | LEXICON PHARMACEUTICALS, INC. | 2004-10-19 | — | — | US | disclosed |
| US-20040171656-A1 | Novel PPAR-gamma agonists as agents for the treatment of type II diabetes | KOLB HARTMUTH C (US) | 2004-09-02 | — | — | US | disclosed |
| EP-1409487-A1 | PTERIDINONES AS KINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20030135050-A1 | One step synthesis of 1,2,3-triazole carboxylic acids | LEXICON PHARMACEUTICALS, INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030130286-A1 | Pteridinones as kinase inhibitors | DENNY WILLIAM ALEXANDER (NZ) | 2003-07-10 | — | — | US | disclosed |
| US-20030073668-A1 | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors | BOOTH RICHARD JOHN (US) | 2003-04-17 | — | — | US | disclosed |
| EP-1254137-A1 | PYRIDO 2,3-d]PYRIMIDINE-2,7-DIAMINE KINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1173408-A1 | PPAR-(GAMMA) AGONISTS AS AGENTS FOR THE TREATMENT OF TYPE II DIABETES | Coelacanth Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| EP-1150687-A2 | METHODS FOR ANTI-TUMOR THERAPY | Cellpath, Inc. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001055147-A1 | PYRIDO[2,3-d]PYRIMIDINE-2,7-DIAMINE KINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001019825-A1 | PTERIDINONES AS KINASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2001-03-22 | — | — | WO | disclosed |
| WO-2000063161-A1 | PPAR-(GAMMA) AGONISTS AS AGENTS FOR THE TREATMENT OF TYPE II DIABETES | COELACANTH CORPORATION (US) | 2000-10-26 | — | — | WO | disclosed |
| WO-2000047215-A2 | METHODS FOR ANTI-TUMOR THERAPY | CELLPATH, INC. (US) | 2000-08-17 | — | — | WO | disclosed |