SCHEMBL5518499

SCHEMBL5518499

O=C(O)C[C@@H](O)[C@H](O)[C@H](O)COP(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PGD P52209 4/20 0.58
▸ PGK1 P00558 1/20 0.52
▸ PGK2 P07205 1/20 0.52
▸ MPI P34949 1/20 0.48
▸ SLC22A6 Q4U2R8 1/20 0.34
▸ FOLH1 Q04609 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5518494 1.00 PGD (0.58) PGDPGK1PGK2MPISLC22A6
SCHEMBL20475921 1.00 PGD (0.58) PGDPGK1PGK2MPISLC22A6
SCHEMBL7748001 1.00 PGD (0.58) PGDPGK1PGK2MPISLC22A6
SCHEMBL7063376 0.98 PGD (0.56) PGDPGK1PGK2MPISLC22A6
SCHEMBL7061119 0.98 PGD (0.56) PGDPGK1PGK2MPISLC22A6
SCHEMBL7063015 0.98 PGD (0.56) PGDPGK1PGK2MPISLC22A6
SCHEMBL7063006 0.96 PGD (0.55) PGDPGK1PGK2MPI
SCHEMBL7063008 0.96 PGD (0.55) PGDPGK1PGK2MPI
SCHEMBL321570 0.85 PGD (0.55) PGDPGK1PGK2MPI
SCHEMBL2619139 0.85 PGD (0.55) PGDPGK1PGK2MPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583258-B1 Transesterification catalyst is a salt of adenosine 5'-monophosphate or 2-deoxy-6-phosphogluconic acid; diaryl carbonate with a dihydroxy aromatic compound; bisphenol A with diphenyl carbonate GENERAL ELECTRIC COMPANY 2003-06-24 — — US claimed
EP-4650780-A2 COMPOSITIONS AND METHODS FOR MODULATING CIRCULATING FACTORS Flagship Pioneering Innovations VII, LLC (US) 2025-11-19 — — EP disclosed
US-20250320254-A1 Compositions and Methods for Modulating Circulating Factors FLAGSHIP PIONEERING INNOVATIONS VII LLC (US) 2025-10-16 — — US disclosed
CN-120035678-A Compositions and methods for modulating circulation factors 旗舰创业创新第七有限责任公司 2025-05-23 — — CN disclosed
EP-4532768-A2 COMPOSITIONS AND METHODS FOR MODULATING CIRCULATING FACTORS Flagship Pioneering Innovations VII, LLC (US) 2025-04-09 — — EP disclosed
WO-2023230578-A2 COMPOSITIONS AND METHODS FOR MODULATING CIRCULATING FACTORS FLAGSHIP PIONEERING INNOVATIONS VII, LLC (US) 2023-11-30 — — WO disclosed
US-20130332133-A1 Classification of Protein Sequences and Uses of Classified Proteins RAMOT AT TEL AVIV UNIVERSITY LTD. (IL) 2013-12-12 — — US disclosed
US-20070042030-A1 Preparation for the application of agents in mini-droplets IDEA AG (DE) 2007-02-22 — — US disclosed
US-20050191627-A1 Enzymes INCYTE CORPORATION (US) 2005-09-01 — — US disclosed
US-20050118594-A1 Enzymes CHAWLA NARINDER K (US) 2005-06-02 — — US disclosed
WO-2003072729-A2 ENZYMES INCYTE CORPORATION (US) 2003-09-04 — — WO disclosed
WO-2003052075-A2 ENZYMES INCYTE GENOMICS, INC. (US) 2003-06-26 — — WO disclosed
EP-1320585-A2 OXIDOREDUCTASES Incyte Genomics, Inc. (US) 2003-06-25 — — EP disclosed
US-6583258-B1 Transesterification catalyst is a salt of adenosine 5'-monophosphate or 2-deoxy-6-phosphogluconic acid; diaryl carbonate with a dihydroxy aromatic compound; bisphenol A with diphenyl carbonate GENERAL ELECTRIC COMPANY 2003-06-24 — — US disclosed
WO-2003042357-A2 ENZYMES INCYTE GENOMICS, INC. (US) 2003-05-22 — — WO disclosed
WO-2002083873-A2 ENZYMES INCYTE GENOMICS, INC. (US) 2002-10-24 — — WO disclosed
WO-2002064795-A2 PUTATIVE HUMAN ENZYMES INCYTE GENOMICS, INC. (US) 2002-08-22 — — WO disclosed
WO-2002050284-A2 OXIDOREDUCTASES INCYTE GENOMICS, INC. (US) 2002-06-27 — — WO disclosed
WO-2002026951-A2 OXIDOREDUCTASES INCYTE GENOMICS INC (US) 2002-04-04 — — WO disclosed
US-6165500-A Preparation for the application of agents in mini-droplets IDEA AG (DE) 2000-12-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070042030-A1 Preparation for the application of agents in mini-droplets FABP4, NPC1L1, LIPA PGD 3137/4885PGK1 3003/4885PGK2 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback