Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | VDR | P11473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18073625 | 0.74 | TDP1 (0.53) | TDP1CASP3LMNAALDH1A1KMT2A | |
| SCHEMBL20022621 | 0.74 | TDP1 (0.53) | TDP1CASP3LMNAALDH1A1KMT2A | |
| SCHEMBL5514761 | 0.72 | TDP1 (0.53) | TDP1CASP3LMNAALDH1A1KDM4E | |
| SCHEMBL10391190 | 0.72 | KMT2A (0.43) | CASP3ALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL5514759 | 0.72 | TDP1 (0.53) | TDP1CASP3LMNAALDH1A1KDM4E | |
| SCHEMBL15081352 | 0.71 | TDP1 (0.50) | TDP1CASP3LMNAALDH1A1KMT2A | |
| SCHEMBL5524122 | 0.71 | LMNA (0.53) | TDP1CASP3LMNAALDH1A1KMT2A | |
| SCHEMBL30630014 | 0.70 | ALDH1A1 (0.48) | CASP3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL21070623 | 0.70 | ALDH1A1 (0.48) | CASP3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL166122 | 0.69 | TDP1 (0.57) | TDP1CASP3LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205331-B2 | Fungicidal carboxamides | BASARAB GREGORY STEVEN | 2007-04-17 | — | — | US | disclosed |
| US-7135585-B2 | Fungicidal carboxamides | BASARAB GREGORY STEVEN | 2006-11-14 | — | — | US | disclosed |
| US-20060178425-A1 | FUNGICIDAL CARBOXAMIDES | BASARAB GREGORY S | 2006-08-10 | — | — | US | disclosed |
| US-20060025472-A1 | FUNGICIDAL CARBOXAMIDES | BASARAB GREGORY S | 2006-02-02 | — | — | US | disclosed |
| US-6642392-B1 | Pyrrole derivatives | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2003-11-04 | — | — | US | disclosed |
| US-6251947-B1 | CERTAIN N-(ARYLPROPYL), N-(ARYLOXYETHYL), AND N-(ARYLALLYL)-CARBOXAMIDES, THEIR AGRICULTURALLY SUITABLE SALTS USED AS FUNGICIDE TO CONTROL PLANT DISEASE BY APPLYING AN EFFECTIVE AMOUNT ON THE PLANT | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2001-06-26 | — | — | US | disclosed |
| WO-1998033765-A1 | FUNGICIDAL CARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178425-A1 | FUNGICIDAL CARBOXAMIDES | CBR3, CBR1, CYC1 | TDP1 877/4885CASP3 82/4885LMNA 1695/4885 |
| US-20060025472-A1 | FUNGICIDAL CARBOXAMIDES | CBR3, CBR1, CYC1 | TDP1 954/4885CASP3 176/4885LMNA 2087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.