SCHEMBL5518940

SCHEMBL5518940

O=C(O)c1ccccc1NCC(C(=O)O)(C(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.57
HPGD P15428 3/20 0.57
HSD17B10 Q99714 3/20 0.57
KDM4E B2RXH2 2/20 0.56
AGTR1 P30556 1/20 0.56
RAB9A P51151 1/20 0.56
POLB P06746 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
FABP4 P15090 2/20 0.47
KMT2A Q03164 4/20 0.46
CYP1A2 P05177 1/20 0.46
CLCN2 P51788 1/20 0.45
CFD P00746 1/20 0.45
ALOX15 P16050 1/20 0.45
FABP3 P05413 1/20 0.45
FABP5 Q01469 1/20 0.45
PLK1 P53350 1/20 0.44
MEN1 O00255 2/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5511458 0.83 ALDH1A1 (0.63) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL31056504 0.82 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL6112484 0.82 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL15635072 0.82 ALDH1A1 (0.57) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL5508912 0.80 ALDH1A1 (0.59) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL15635678 0.79 ALDH1A1 (0.54) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL5512467 0.79 ALDH1A1 (0.58) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL1170114 0.79 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL8689214 0.79 ALDH1A1 (0.79) ALDH1A1HPGDHSD17B10KDM4EAGTR1
SCHEMBL29365352 0.79 ALDH1A1 (0.67) ALDH1A1HPGDHSD17B10KDM4EAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed