Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.48 |
| ▸ | FABP4 | P15090 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | FABP3 | P05413 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112484 | 1.00 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL15635678 | 0.86 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL10887861 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL15635830 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL5518940 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL15635072 | 0.82 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL8884667 | 0.81 | KDM4E (0.62) | ALDH1A1HPGDHSD17B10KDM4EPOLB | |
| SCHEMBL17182409 | 0.79 | ADRA1D (0.52) | ALDH1A1HSD17B10KDM4EPOLBL3MBTL1 | |
| SCHEMBL1170114 | 0.79 | ALDH1A1 (0.67) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 | |
| SCHEMBL8689214 | 0.79 | ALDH1A1 (0.79) | ALDH1A1HPGDHSD17B10KDM4EAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |