SCHEMBL5518973

SCHEMBL5518973

O=C(O)CCCCCNc1ccccc1C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.76
HSD17B10 Q99714 4/20 0.76
HPGD P15428 3/20 0.76
KDM4E B2RXH2 3/20 0.61
AGTR1 P30556 1/20 0.51
RAB9A P51151 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPT P10636 2/20 0.51
AKR1C3 P42330 1/20 0.51
AKR1C2 P52895 1/20 0.51
AKR1C1 Q04828 1/20 0.51
CDC25A P30304 1/20 0.49
CDC25B P30305 1/20 0.49
POLB P06746 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
TBXA2R P21731 1/20 0.49
KDM6B O15054 2/20 0.48
KDM4C Q9H3R0 2/20 0.48
PLK1 P53350 1/20 0.48
APEX1 P27695 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5514066 1.00 ALDH1A1 (0.76) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5510920 0.98 ALDH1A1 (0.78) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5515007 0.93 ALDH1A1 (0.81) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5512532 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL6152410 0.85 ALDH1A1 (0.59) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL3475665 0.84 PLK1 (0.66) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5694119 0.84 PLK1 (0.66) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL5272720 0.84 PLK1 (0.66) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL11432358 0.84 PLK1 (0.66) ALDH1A1HSD17B10HPGDKDM4EAGTR1
SCHEMBL11430175 0.84 PLK1 (0.66) ALDH1A1HSD17B10HPGDKDM4EAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470258-B1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2013-08-28 EP disclosed
US-7250456-B2 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2007-07-31 US disclosed
US-20050148702-A1 Composition and its use for imparting water repellency to leather or furskins, textiles and other fibrous materials TFL LEDERTECHNIK GMBH (DE) 2005-07-07 US disclosed
EP-1470258-A1 COMPOSITION AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL Ledertechnik GmbH (DE) 2004-10-27 EP disclosed
WO-2003064707-A1 COMPOSITIONS AND ITS USE FOR IMPARTING WATER REPELLENCY TO LEATHER OR FURSKINS, TEXTILES AND OTHER FIBROUS MATERIALS TFL LEDERTECHNIK GMBH (DE) 2003-08-07 WO disclosed