Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.50 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519161 | 1.00 | KAT6A (0.50) | KAT6AHSD17B13ARNR1H4 | |
| SCHEMBL5526173 | 0.89 | AR (0.45) | HSD17B13AR | |
| SCHEMBL14451504 | 0.89 | CXCR3 (0.43) | KAT6AHSD17B13AR | |
| SCHEMBL5526168 | 0.89 | AR (0.45) | HSD17B13AR | |
| SCHEMBL5523321 | 0.83 | HDAC3 (0.51) | ARNR1H4 | |
| SCHEMBL5521806 | 0.83 | HDAC3 (0.51) | ARNR1H4 | |
| SCHEMBL5521812 | 0.83 | HDAC3 (0.51) | ARNR1H4 | |
| SCHEMBL14425743 | 0.80 | KDM4E (0.54) | — | |
| SCHEMBL5519098 | 0.79 | GABRA5 (0.48) | NR1H4 | |
| SCHEMBL5519092 | 0.79 | GABRA5 (0.48) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | PFIZER, INC. | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167452-A1 | Therapeutic amide derivatives | GRIN1, GRIN2B, GRIN3A | KAT6A 279/4885HSD17B13 3334/4885AR 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.