Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 9/20 | 0.38 |
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL2041686 | 0.98 | TSHR (0.46) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL366479 | 0.98 | TSHR (0.44) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL27471140 | 0.96 | TSHR (0.43) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL27707661 | 0.96 | TSHR (0.43) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL4171532 | 0.96 | TSHR (0.43) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL27471139 | 0.96 | TSHR (0.43) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL5864144 | 0.96 | TSHR (0.47) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL28579868 | 0.95 | TSHR (0.46) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL31031688 | 0.95 | TSHR (0.46) | TSHRMEN1KMT2ACES2POLB | |
| Sulfuric Acid SCHEMBL515836 | 0.91 | TSHR (0.40) | TSHRMEN1KMT2ACES2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3845642-B1 | PROTEASE VARIANTS AND USES THEREOF | DANISCO US INC (US) | 2023-08-09 | — | — | EP | disclosed |
| CN-114729125-A | Composition for preparing release coating | 美国陶氏有机硅公司 | 2022-07-08 | — | — | CN | disclosed |
| EP-3845642-A1 | PROTEASE VARIANTS AND USES THEREOF | Danisco US Inc. (US) | 2021-07-07 | — | — | EP | disclosed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-3356356-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2021-05-26 | — | — | EP | disclosed |
| EP-3452584-B1 | PROTEASE VARIANTS AND USES THEREOF | DANISCO US INC (US) | 2021-01-06 | — | — | EP | disclosed |
| CN-107207740-B | Method for preparing functionalized particles | 美国陶氏有机硅公司 | 2020-03-17 | — | — | CN | disclosed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. | 2019-06-13 | — | — | US | disclosed |
| US-20190136218-A1 | PROTEASE VARIANTS AND USES THEREOF | DANISCO US INC (US) | 2019-05-09 | — | — | US | disclosed |
| US-7278904-B2 | Method of abrading a workpiece | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-10-09 | — | — | US | disclosed |
| EP-1697084-A1 | METHOD OF ABRADING A WORKPIECE | 3M Innovative Properties Company (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005053904-A1 | METHOD OF ABRADING A WORKPIECE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-16 | — | — | WO | disclosed |
| US-20050113005-A1 | Method of abrading a workpiece | 3M INNOVATIVE PROPERTIES COMPANY | 2005-05-26 | — | — | US | disclosed |
| US-6770123-B2 | PROLONGED ADHERENCE; MATTE APPEARANCE; WEATHER RESISTANCE | CLARIANT FINANCE (BVI) LIMITED (VG) | 2004-08-03 | — | — | US | disclosed |
| US-20040016364-A1 | PROTECTIVE COATINGS HAVING BRANCHED TRIMETHYLSILYLATED ALKYLSILSESQUIOXANE EMULSIONS | SIVANCE, LLC | 2004-01-29 | — | — | US | disclosed |
| EP-0837104-A2 | Ammonium siloxane emulsions and their use as fiber treatment agents | DOW CORNING CORPORATION (US) | 1998-04-22 | — | — | EP | disclosed |
| US-5707435-A | SOFTENING AGENTS | DOW CORNING CORPORATION (US) | 1998-01-13 | — | — | US | disclosed |
| US-3993684-A | PHOTOSENSITIVE ACRYLIC ESTER POLYMERS | WESTERN LITHO PLATE & SUPPLY CO. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3955032-A | METAL OXIDES, CHLORINATED OR CHLOROBROMINATED CYCLOPENTADIENO COMPOUNDS | WHITE CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | TSHR 2580/4885MEN1 1052/4885KMT2A 3630/4885 |
| US-20190177308-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM6, TRPM4 | TSHR 2031/4885MEN1 1247/4885KMT2A 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.