Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 7/20 | 0.62 |
| ▸ | CTSL | P07711 | 6/20 | 0.62 |
| ▸ | CTSB | P07858 | 5/20 | 0.62 |
| ▸ | CTSK | P43235 | 6/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6183576 | 0.87 | CTSS (0.65) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6184079 | 0.86 | CTSS (0.67) | CTSSCTSLCTSBCTSK | |
| SCHEMBL1151498 | 0.85 | CTSS (0.65) | CTSSCTSLCTSBCTSKTSHR | |
| SCHEMBL19920764 | 0.85 | CTSB (0.48) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL8981148 | 0.83 | CTSS (0.67) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL1839379 | 0.83 | CTSS (0.67) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL8981271 | 0.83 | CTSS (0.67) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL8981223 | 0.83 | CTSS (0.67) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL8981228 | 0.83 | CTSS (0.67) | CTSSCTSLCTSBCTSKNPC1 | |
| SCHEMBL2715828 | 0.83 | CTSS (0.52) | CTSSCTSLCTSBCTSKCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | CTSS 3342/4885CTSL 3370/4885CTSB 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.