Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012964 | 0.92 | CYP1A2 (0.46) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL9022447 | 0.87 | — | — | |
| SCHEMBL548628 | 0.79 | LMNA (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL9635796 | 0.79 | LMNA (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL9637022 | 0.79 | LMNA (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| Disulfoxidie Bis(3,3 Chloro Benzene) SCHEMBL22335884 | 0.79 | LMNA (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL23569839 | 0.74 | LMNA (0.44) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL8242027 | 0.74 | LMNA (0.44) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL15109075 | 0.74 | LMNA (0.44) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL196857 | 0.74 | LMNA (0.44) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4102907-A | Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione | THE UPJOHN COMPANY (US) | 1978-07-25 | — | — | US | claimed |
| CN-117326994-B | Preparation method of perfluoroalkyl aryl sulfide | 西安近代化学研究所 | 2026-05-15 | — | — | CN | disclosed |
| CN-115286543-B | Process for preparing 4,4' -dichloro diphenyl sulfone by utilizing perfluoroalkyl sulfonic acid ionic liquid | 富海(东营)新材料科技有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-115286543-A | Process for preparing 4,4' -dichlorodiphenyl sulfone by utilizing perfluoroalkyl sulfonic acid ionic liquid | 富海(东营)新材料科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-110396116-B | [ N, O ] bidentate nickel and palladium complex of ketone-imidazoline-2-imine ligand, and preparation method and application thereof | 东华大学 | 2020-07-28 | — | — | CN | disclosed |
| US-20190119280-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT AND PDGFR | BLUEPRINT MEDICINES CORPORATION | 2019-04-25 | — | — | US | disclosed |
| EP-1973901-B1 | HYDANTOIN DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISORDERS | MERCK SHARP & DOHME (US) | 2014-12-17 | — | — | EP | disclosed |
| US-7998958-B2 | Substituted N-arylsulfonylheterocyclic amines as gamma-secretase inhibitors | SCHERING CORPORATION (US) | 2011-08-16 | — | — | US | disclosed |
| EP-2070914-B1 | New antagonist derivatives of the vitronectin receptor, method for their preparation, their application as medicine and pharmaceutical compositions containing them | GALAPAGOS SAS (FR) | 2011-08-03 | — | — | EP | disclosed |
| US-7763613-B2 | Substituted N-arylsulfonylheterocyclic amines as gamma-secretase inhibitors | SCHERING CORPORATION (US) | 2010-07-27 | — | — | US | disclosed |
| EP-0552553-A1 | Sulfonimidamides as antineoplastic agents | ELI LILLY AND COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| US-4240974-A | 1,2,3,4,9,9-HEXAHALO-1,4-DIHYDRO-1,4-METHANO-NAPHTHALENE-5,8 -DISULFONATE | LITTLE JULIAN R (US) | 1980-12-23 | — | — | US | disclosed |
| US-4174457-A | Carbamate | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |
| US-4102907-A | Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione | THE UPJOHN COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4080408-A | FIRE RETARDANTS | UNIROYAL, INC. (US) | 1978-03-21 | — | — | US | disclosed |
| US-4066619-A | STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4058568-A | FIRE RETARDANT | UNIROYAL, INC. (US) | 1977-11-15 | — | — | US | disclosed |
| US-4055540-A | STABILIZERS FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1977-10-25 | — | — | US | disclosed |
| US-4009200-A | FIREPROOFING POLYMERS | UNIROYAL, INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3950374-A | INSECTICIDE, NEMATOCIDE, MITICIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190119280-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT AND PDGFR | KIT, PDGFRA, PDGFRB | LMNA 848/4885CYP2A6 4450/4885MAPK1 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.