Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9635796 | 1.00 | LMNA (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL548628 | 1.00 | LMNA (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL9637222 | 0.92 | CYP1A2 (0.48) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL197577 | 0.92 | CYP1A2 (0.48) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL197578 | 0.89 | TSHR (0.48) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL7937426 | 0.87 | MAPT (0.41) | LMNACYP2A6ALDH1A1TSHRCYP1A2 | |
| SCHEMBL10923598 | 0.87 | MEN1 (0.50) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL28881835 | 0.87 | CES2 (0.45) | LMNACYP2A6CES1CES2MEN1 | |
| SCHEMBL9635825 | 0.87 | CYP2A6 (0.38) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 | |
| SCHEMBL7935399 | 0.87 | MAPK1 (0.46) | LMNACYP2A6MAPK1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144004-A | Heat resistance, selective degradation, reaction of halogen substituted sulfones and sulfoxides and alkali metal sulfides | PHILLIPS PETROLEUM COMPANY (US) | 1992-09-01 | — | — | US | disclosed |