Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333352 | 0.85 | ALOX5 (0.58) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333454 | 0.80 | MEN1 (0.74) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333666 | 0.79 | PTGES (0.64) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333866 | 0.78 | MEN1 (0.59) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL334043 | 0.76 | PTGES (0.61) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333699 | 0.75 | MAPT (0.61) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333920 | 0.75 | KMT2A (0.57) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333953 | 0.75 | KMT2A (0.60) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333739 | 0.74 | KMT2A (0.62) | MEN1KMT2AALOX5TSHRNPSR1 | |
| SCHEMBL333681 | 0.74 | ALOX5 (0.52) | MEN1KMT2AALOX5TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077366-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |