Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16108558 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL7226795 | 0.81 | MAPT (0.50) | ALDH1A1HPGDGAAKMT2ALMNA | |
| SCHEMBL11436533 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL1244426 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL4014038 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL12139528 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL20496906 | 0.79 | HPGD (0.53) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| Hydrochloric Acid SCHEMBL28128903 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EGAAKMT2A | |
| SCHEMBL27805137 | 0.78 | TSHR (0.57) | ALDH1A1HPGDKDM4EKMT2AHTT | |
| SCHEMBL16108407 | 0.78 | MAPT (0.44) | ALDH1A1HPGDKDM4EGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111333593-B | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-111333593-A | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-111333593-B | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-112321474-A | Synthesis process of tricyclazole intermediate o-methyl phenylthiosemicarbazide | 江苏长青农化股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-111333593-A | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2020-06-26 | — | — | CN | disclosed |
| EP-2695911-B1 | PROCESS FOR PRODUCING RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2018-06-27 | — | — | EP | disclosed |
| US-9822246-B2 | Process for producing rubber composition | BRIDGESTONE CORPORATION (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9353089-B2 | Compositions and methods for the treatment of malaria | SAINT LOUIS UNIVERSITY (US) | 2016-05-31 | — | — | US | disclosed |
| WO-2014160775-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA | SAINT LOUIS UNIVERSITY (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140296532-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-02 | — | — | US | disclosed |
| US-20140171580-A1 | PROCESS FOR PRODUCING RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2014-06-19 | — | — | US | disclosed |
| EP-2695911-A1 | PROCESS FOR PRODUCING RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2014-02-12 | — | — | EP | disclosed |
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
| EP-1085009-B1 | INDAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6486178-B1 | Indane derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-11-26 | — | — | US | disclosed |
| CN-1376155-A | Thiourea and isothiourea derivatives for inhibiting RAS-transformed cell growth | YUHAN CORP (KR) | 2002-10-23 | — | — | CN | disclosed |
| EP-1085009-A1 | INDAN DERIVATIVES | Nissan Chemical Industries, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | ALDH1A1 2069/4885HPGD 3176/4885KDM4E 1012/4885 |
| US-20140296532-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA | BACE2, DNPEP, ACE | ALDH1A1 1822/4885HPGD 1696/4885KDM4E 762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.