⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256036 | 1.00 | — | — | |
| SCHEMBL22182586 | 1.00 | — | — | |
| SCHEMBL23198921 | 0.90 | HCAR2 (0.43) | — | |
| SCHEMBL23671880 | 0.90 | HCAR2 (0.43) | — | |
| SCHEMBL23671855 | 0.90 | HCAR2 (0.43) | — | |
| SCHEMBL23671857 | 0.90 | HCAR2 (0.43) | — | |
| SCHEMBL13618771 | 0.83 | HCAR2 (0.48) | — | |
| SCHEMBL21392011 | 0.80 | MAPT (0.51) | — | |
| SCHEMBL20634195 | 0.80 | MAPT (0.51) | — | |
| SCHEMBL3688382 | 0.80 | MAPT (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633704-A2 | INTERMEDIATES USEFUL IN THE SYNTHESIS OF HIV-PROTEASE INHIBITORS AND METHODS FOR PREPARING THE SAME | PFIZER INC. (US) | 2006-03-15 | — | — | EP | claimed |
| US-20050250949-A1 | Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same | AGOURON PHARMACEUTICALS INC. | 2005-11-10 | — | — | US | claimed |
| WO-2004099129-A2 | INTERMEDIATES USEFUL IN THE SYNTHESIS OF HIV-PROTEASE INHIBITORS AND METHODS FOR PREPARING THE SAME | PFIZER INC. (US) | 2004-11-18 | — | — | WO | claimed |
| US-4672068-A | Antihypertensive 1,4-dihydropyridines having a conjugated ester | FUJIREBIO KABUSHIKI KAISHA (JP) | 1987-06-09 | — | — | US | claimed |
| CN-114907514-A | Multifunctional fiber and preparation method and application thereof | 北京洁尔爽高科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| WO-2022057387-A1 | 3-(3-ARYL/HETEROARYL-4-THIAZOLINONE)-N-ARYL/HETEROCYCLIC BENZAMIDE COMPOUND AND USE THEREOF | 上海鸿恒生物医药科技有限公司 | 2022-03-24 | — | — | WO | disclosed |
| US-7173059-B2 | Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same | AGOURON PHARMACEUTICALS, INC. (US) | 2007-02-06 | — | — | US | disclosed |
| CN-1819993-A | Intermediates for the synthesis of HIV-protease inhibitors and processes for their preparation | PFIZER (US) | 2006-08-16 | — | — | CN | disclosed |
| EP-1633704-A2 | INTERMEDIATES USEFUL IN THE SYNTHESIS OF HIV-PROTEASE INHIBITORS AND METHODS FOR PREPARING THE SAME | PFIZER INC. (US) | 2006-03-15 | — | — | EP | disclosed |
| US-20050250949-A1 | Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same | AGOURON PHARMACEUTICALS INC. | 2005-11-10 | — | — | US | disclosed |
| WO-2004099129-A2 | INTERMEDIATES USEFUL IN THE SYNTHESIS OF HIV-PROTEASE INHIBITORS AND METHODS FOR PREPARING THE SAME | PFIZER INC. (US) | 2004-11-18 | — | — | WO | disclosed |