SCHEMBL5523819

SCHEMBL5523819

CCCCOc1nc(N)c2[nH]c(=O)n(CCS(=O)(=O)c3cccc(OC(C)=O)c3)c2n1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17473815 0.88 TLR7 (0.54) TLR7
SCHEMBL2389742 0.87 TLR7 (0.52) TLR7
SCHEMBL17473799 0.86 TLR7 (0.53) TLR7
SCHEMBL17473801 0.86 TLR7 (0.52) TLR7
SCHEMBL5522524 0.86 TLR7 (0.62) TLR7
SCHEMBL2389739 0.85 TLR7 (0.55) TLR7
SCHEMBL2389747 0.85 TLR7 (0.74) TLR7
SCHEMBL5964145 0.85 TLR7 (0.51) TLR7
SCHEMBL2386573 0.84 TLR7 (0.62) TLR7
SCHEMBL5522471 0.84 TLR7 (0.56) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1728793-B1 9-SUBSTITUTED 8-OXOADENINE COMPOUND SUMITOMO DAINIPPON PHARMA CO LTD (JP) 2016-02-03 EP disclosed
US-20070190071-A1 9-Substituted 8-oxoadenine compound DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070190071-A1 9-Substituted 8-oxoadenine compound IFNAR1, IL5, IFNG TLR7 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.