SCHEMBL5525267

SCHEMBL5525267

O=C1NC(=O)C(=Cc2ccccc2)O1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
HPGD P15428 4/20 0.52
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
STK17B O94768 1/20 0.47
LMNA P02545 2/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PIM1 P11309 1/20 0.46
PIM3 Q86V86 1/20 0.46
PIM2 Q9P1W9 1/20 0.46
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MITF O75030 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5525263 1.00 MEN1 (0.65) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL8172890 0.93 MEN1 (0.58) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL8172892 0.93 MEN1 (0.58) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL8180304 0.90 MEN1 (0.54) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL8180300 0.90 MEN1 (0.54) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL28354600 0.83 ELANE (0.60) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL6618501 0.81 MEN1 (0.61) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL6618504 0.81 MEN1 (0.61) MEN1KMT2AHPGDKDM4EALDH1A1
SCHEMBL6970152 0.81 METAP1 (0.55) MEN1KMT2AHPGDALDH1A1TDP1
SCHEMBL6970148 0.81 METAP1 (0.55) MEN1KMT2AHPGDALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5140130-A None JP disclosed
CN-119019702-A Can catalyze low concentration CO2Metal and amino simultaneous functionalization imidazolyl porous organic polymer converted in situ, preparation method and application 桂林电子科技大学 2024-11-26 CN disclosed
US-7262252-B2 Nonlinear optical materials comprising fluorine-containing polymer DAIKIN INDUSTRIES, LTD. (JP) 2007-08-28 US disclosed
US-20050004253-A1 Nonlinear optical materials comprising fluorine-containing polymer DAIKIN INDUSTRIES, LTD 2005-01-06 US disclosed
EP-1406116-A1 NONLINEAR OPTICAL MATERIAL CONTAINING FLUOROPOLYMER Daikin Industries, Ltd. (JP) 2004-04-07 EP disclosed
US-5306822-A Mono-, di- or tri-methoxyphenylmethylene-2-thioxo-4-oxazolidinone as antihistamines WARNER-LAMBERT COMPANY (US) 1994-04-26 US disclosed
EP-0343643-B1 Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents WARNER LAMBERT CO (US) 1994-03-23 EP disclosed
JP-H05140130-A PRODUCTION OF 5-BENZYLIDENEOXAZOLIDINE-2,4-DIONE DERIVATIVE FUJI PHOTO FILM CO LTD 1993-06-08 JP disclosed
US-5208250-A Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents WARNER-LAMBERT COMPANY (US) 1993-05-04 US disclosed
EP-0343643-A2 Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents WARNER-LAMBERT COMPANY (US) 1989-11-29 EP disclosed
US-4314023-A AZO-METHINE DYES KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1982-02-02 US disclosed