Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.70 |
| ▸ | KDM5A | P29375 | 9/20 | 0.70 |
| ▸ | KDM4A | O75164 | 2/20 | 0.66 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.66 |
| ▸ | KDM5C | P41229 | 1/20 | 0.62 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584728 | 0.98 | KDM4C (0.68) | KDM4CKDM5AKDM4APHF8KDM5C | |
| Hydrochloric Acid SCHEMBL11629176 | 0.98 | KDM4C (0.68) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL365810 | 0.93 | KDM4C (0.71) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL5984578 | 0.91 | KDM4C (0.72) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL8359768 | 0.91 | KDM4C (0.72) | KDM4CKDM5AKDM4APHF8KDM5C | |
| Hydrochloric Acid SCHEMBL369126 | 0.91 | KDM4C (0.69) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL8341418 | 0.91 | KDM4C (0.72) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL11587594 | 0.91 | KDM4C (0.72) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL8626544 | 0.91 | KDM4C (0.69) | KDM4CKDM5AKDM4APHF8KDM5C | |
| SCHEMBL29380393 | 0.91 | KDM4C (0.72) | KDM4CKDM5AKDM4APHF8KDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715631-B1 | PROCESS FOR PRODUCING N-AMINO-1-HYDROXY-ALKYL-IDENE-1,1-BISPHOSPHONIC ACIDS | MERCK & CO INC (US) | 1997-11-19 | — | — | EP | claimed |
| US-5648491-A | Process for producing n-amino-1-hydroxy-alkyl-idene-1,1-bisphosphonic acids | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | claimed |
| EP-0715631-A1 | PROCESS FOR PRODUCING N-AMINO-1-HYDROXY-ALKYL-IDENE-1,1-BISPHOSPHONIC ACIDS | MERCK & CO. INC. (US) | 1996-06-12 | — | — | EP | claimed |
| WO-1995006052-A1 | PROCESS FOR PRODUCING N-AMINO-1-HYDROXY-ALKYL-IDENE-1,1-BISPHOSPHONIC ACIDS | MERCK & CO., INC. (US) | 1995-03-02 | — | — | WO | claimed |
| US-11708317-B2 | Process for the catalytic decarboxylative cross-ketonization of aryl and aliphatic carboxylic acid | RHODIA OPERATIONS (FR) | 2023-07-25 | — | — | US | disclosed |
| US-20210228737-A1 | ZWITTERIONIC BIOCOMPATIBLE POLYMERS, METHODS, AND USES THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2021-07-29 | — | — | US | disclosed |
| EP-2379118-B1 | NANOPARTICLE CONTRAST AGENTS FOR DIAGNOSTIC IMAGING | GEN ELECTRIC (US) | 2017-10-18 | — | — | EP | disclosed |
| US-9585974-B2 | Nanoparticle contrast agents for diagnostic imaging | GENERAL ELECTRIC COMPANY (US) | 2017-03-07 | — | — | US | disclosed |
| US-20130012491-A1 | PYRIMIDINE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2013-01-10 | — | — | US | disclosed |
| US-8178712-B2 | Process for the synthesis of Ibandronate sodium | CIPLA LTD. (IN) | 2012-05-15 | — | — | US | disclosed |
| US-8178712-B2 | Process for the synthesis of Ibandronate sodium | CIPLA LTD. (IN) | 2012-05-15 | — | — | US | disclosed |
| US-20120077781-A1 | FLAVIN DERIVATIVES | GADWOOD ROBERT (US) | 2012-03-29 | — | — | US | disclosed |
| EP-2038291-B1 | PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM | CIPLA LTD (IN) | 2010-07-14 | — | — | EP | disclosed |
| WO-2008035367-A2 | PROCESS FOR THE SYNTHESIS OF IBANDRONATE SODIUM | CIPLA LTD. (IN) | 2008-03-27 | — | — | WO | disclosed |
| EP-0715631-B1 | PROCESS FOR PRODUCING N-AMINO-1-HYDROXY-ALKYL-IDENE-1,1-BISPHOSPHONIC ACIDS | MERCK & CO INC (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5648491-A | Process for producing n-amino-1-hydroxy-alkyl-idene-1,1-bisphosphonic acids | MERCK & CO., INC. (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0715631-A1 | PROCESS FOR PRODUCING N-AMINO-1-HYDROXY-ALKYL-IDENE-1,1-BISPHOSPHONIC ACIDS | MERCK & CO. INC. (US) | 1996-06-12 | — | — | EP | disclosed |
| US-5510517-A | Process for producing N-amino-1-hydroxy-alkylidene-1,1-bisphosphonic acids | MERCK & CO., INC. (US) | 1996-04-23 | — | — | US | disclosed |
| WO-1995006052-A1 | PROCESS FOR PRODUCING N-AMINO-1-HYDROXY-ALKYL-IDENE-1,1-BISPHOSPHONIC ACIDS | MERCK & CO., INC. (US) | 1995-03-02 | — | — | WO | disclosed |
| US-4077941-A | PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708317-B2 | Process for the catalytic decarboxylative cross-ketonization of aryl and aliphatic carboxylic acid | JMJD7, PDK2, PIR | KDM4C 279/4885KDM5A 210/4885KDM4A 29/4885 |
| US-20130012491-A1 | PYRIMIDINE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS | S1PR1, S1PR3, S1PR5 | KDM4C 4553/4885KDM5A 3848/4885KDM4A 3873/4885 |
| US-20210228737-A1 | ZWITTERIONIC BIOCOMPATIBLE POLYMERS, METHODS, AND USES THEREOF | ALG1, CD44, PHOSPHO1 | KDM4C 3175/4885KDM5A 3976/4885KDM4A 3886/4885 |
| US-20120077781-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | KDM4C 2018/4885KDM5A 1252/4885KDM4A 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.