Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | NLN | Q9BYT8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8652194 | 0.99 | HTT (0.38) | HTTATMTERTALDH1A1L3MBTL1 | |
| SCHEMBL16458256 | 0.89 | HTT (0.37) | HTTATMALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2608923 | 0.88 | RECQL (0.43) | HTTATMALDH1A1L3MBTL1MEN1 | |
| SCHEMBL7619939 | 0.86 | LARS1 (0.39) | HTTATM | |
| SCHEMBL7619941 | 0.86 | LARS1 (0.39) | HTTATM | |
| SCHEMBL7772829 | 0.86 | HTT (0.37) | HTTATMALDH1A1L3MBTL1SMYD3 | |
| SCHEMBL30399454 | 0.84 | GAA (0.45) | HTTATMALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7624049 | 0.84 | NLN (0.42) | NLN | |
| SCHEMBL15398762 | 0.84 | NLN (0.39) | NLN | |
| SCHEMBL7624042 | 0.84 | NLN (0.42) | NLN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139414-A1 | COMPOSITION FOR TREATING ESOPHAGEAL REFLUX | METIS HEALTHCARE S.R.L. (IT) | 2023-07-27 | — | — | WO | claimed |
| EP-3328409-A1 | COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION | Metis Healthcare S.r.L. (IT) | 2018-06-06 | — | — | EP | claimed |
| WO-2017021816-A1 | COMPOSITION FOR THE INCREASE OF HUMORAL SECRETION | METIS HEALTHCARE S.R.L. (IT) | 2017-02-09 | — | — | WO | claimed |
| EP-1812110-A1 | APPARATUS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | Dermaglaia Ltd. (GB) | 2007-08-01 | — | — | EP | claimed |
| WO-2006040597-A1 | APPARATUS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | DERMAGLAIA LTD (GB) | 2006-04-20 | — | — | WO | claimed |
| EP-0684944-A1 | COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID | EXSYMOL S.A.M. (MC) | 1995-12-06 | — | — | EP | claimed |
| WO-1994019325-A1 | COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID | EXSYMOL SOCIETE ANONYME MONEGASQUE (MC) | 1994-09-01 | — | — | WO | claimed |
| US-20230203016-A1 | DICARBOXYLIC ACID BISAMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING DICARBOXYLIC ACID BISAMIDE DERIVATIVES | NEBOLSIN, VLADIMIR EVGENIEVICH (RU) | 2023-06-29 | — | — | US | disclosed |
| CN-110913957-B | Cosmetic composition comprising an essential oil of Helichrysum and an extract of oregano | M&L实验室 | 2022-12-02 | — | — | CN | disclosed |
| US-20220324843-A1 | DICARBOXYLIC ACID BISAMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING DICARBOXYLIC ACID BISAMIDE DERIVATIVES | NEBOLSIN, VLADIMIR EVGENIEVICH (RU) | 2022-10-13 | — | — | US | disclosed |
| CN-107106464-B | Antioxidant and antioxidant/UV-preventive cosmetic | 江崎格力高株式会社 | 2020-09-11 | — | — | CN | disclosed |
| CN-107912022-A | Cosmetic composition containing E/Z-2-benzyl indene-5, 6-dimethoxy-3, 3-dimethyl indan-1-one | 西姆莱斯股份公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-104769026-A | Surface modification method and surface-modified elastic body | SUMITOMO RUBBER IND | 2015-07-08 | — | — | CN | disclosed |
| WO-2004028536-A1 | METHOD FOR TOPICAL TREATMENT OF EYE DISEASE AND COMPOSITION AND DEVICE FOR SAID TREATMENT | BABIZHAYEV MARK A (RU) | 2004-04-08 | — | — | WO | disclosed |
| US-5792784-A | A PSEUDO-DIPEPTIDE PRODUCT WHICH IS HISTAMINE OR METHYL-SUBSTITUTED HISTAMINE COUPLED WITH A AMINO ACID; USED IN THERAPEUTICAL, COSMETOLOGICAL APPLICATIONS AND TREATS VISION DEFECT | Babizhayev, Marc (SU) | 1998-08-11 | — | — | US | disclosed |
| EP-0684944-A1 | COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID | EXSYMOL S.A.M. (MC) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019325-A1 | COUPLING PRODUCT OBTAINED FROM HYSTAMINE AND AN AMINO ACID | EXSYMOL SOCIETE ANONYME MONEGASQUE (MC) | 1994-09-01 | — | — | WO | disclosed |
| US-4863903-A | RENIN ENZYME INHIBITORS, HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| US-4719288-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4613676-A | PEPTIDES | CIBA-GEIGY CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203016-A1 | DICARBOXYLIC ACID BISAMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING DICARBOXYLIC ACID BISAMIDE DERIVATIVES | GOT2, HADHA, ACAA2 | HTT 1629/4885ATM 3554/4885TERT 1085/4885 |
| US-20220324843-A1 | DICARBOXYLIC ACID BISAMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHODS FOR PRODUCING DICARBOXYLIC ACID BISAMIDE DERIVATIVES | GOT2, HADHA, ACAA2 | HTT 1629/4885ATM 3554/4885TERT 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.