Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409598 | 0.88 | HTR2A (0.59) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL1133822 | 0.87 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAKMT2A | |
| Ethylene Glycol SCHEMBL5476146 | 0.86 | BCL9 (0.58) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL26374 | 0.85 | GAA (0.65) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL25764 | 0.85 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL24606 | 0.85 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL763025 | 0.85 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL278663 | 0.85 | BCL9 (0.62) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL13069276 | 0.85 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL1421471 | 0.85 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109878-A1 | TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-06-22 | — | — | WO | disclosed |
| US-20070082019-A1 | Photocrosslinked hydrogel surface coatings | CIPHERGEN BIOSYSTEMS INC. | 2007-04-12 | — | — | US | disclosed |
| US-20060292701-A1 | Photocrosslinked hydrogel blend surface coatings | CIPHERGEN BIOSYSTEMS INC. | 2006-12-28 | — | — | US | disclosed |
| US-20060252159-A1 | Photocrosslinked hydrogel blend surface coatings | CIPHERGEN BIOSYSTEMS INC. | 2006-11-09 | — | — | US | disclosed |
| EP-1680664-A2 | REACTIVE POLYURETHANE-BASED POLAMERS | Ciphergen Biosystems, Inc. (US) | 2006-07-19 | — | — | EP | disclosed |
| US-7045366-B2 | Photocrosslinked hydrogel blend surface coatings | CIPHERGEN BIOSYSTEMS, INC. (US) | 2006-05-16 | — | — | US | disclosed |
| US-20050112650-A1 | Reactive polyurethane-based polymers | CIPHERGEN BIOSYSTEMS, INC. (US) | 2005-05-26 | — | — | US | disclosed |
| WO-2005039724-A2 | REACTIVE POLYURETHANE-BASED POLAMERS | CIPHERGEN BIOSYSTEM, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
| US-20050059086-A1 | Photocrosslinked hydrogel blend surface coatings | CIPHERGEN BIOSYSTEMS INC. | 2005-03-17 | — | — | US | disclosed |
| WO-2004076511-A2 | PHOTOCROSSLINKED HYDROGEL SURFACE COATINGS | CIPHERGEN BIOSYSTEMS, INC. (US) | 2004-09-10 | — | — | WO | disclosed |