Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10062012 | 0.95 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL22959846 | 0.95 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL409598 | 0.93 | HTR2A (0.59) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL9910888 | 0.93 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL29192620 | 0.93 | HTR2A (0.51) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL15760612 | 0.92 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL1144551 | 0.92 | MGLL (0.62) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL11998880 | 0.91 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL27882785 | 0.91 | MGLL (0.60) | HTR2ABCL9CTNNB1GAAMGLL | |
| SCHEMBL20466168 | 0.91 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAAMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313794-B1 | ELASTOMERIC FUNCTIONAL BIODEGRADABLE COPOLYESTER AMIDES AND COPOLYESTER URETHANES | CORNELL RES FOUNDATION INC (US) | 2006-11-29 | — | — | EP | claimed |
| US-6503538-B1 | Elastomeric functional biodegradable copolyester amides and copolyester urethanes | CORNELL RESEARCH FOUNDATION, INC. | 2003-01-07 | — | — | US | claimed |
| US-8137700-B2 | Main chain acid-degradable polymers for the delivery of bioactive materials | U.S. DEPARTMENT OF ENERGY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-03 | — | — | US | disclosed |
| US-7408018-B2 | Elastomeric functional biodegradable copolyester amides and copolyester urethanes | CORNELL RESEARCH FOUNDATION, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20070027293-A1 | Elastomeric functional biodegradable copolyester amides and copolyester urethanes | CORNELL RESEARCH FOUNDATION, INC. | 2007-02-01 | — | — | US | disclosed |
| US-6503538-B1 | Elastomeric functional biodegradable copolyester amides and copolyester urethanes | CORNELL RESEARCH FOUNDATION, INC. | 2003-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | CTSA, GAA, CTSB | HTR2A 4460/4885BCL9 2681/4885CTNNB1 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.