Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143663 | 0.95 | DNM1 (0.44) | DNM1LSSLPAR1LPAR3LPAR2 | |
| SCHEMBL21380052 | 0.94 | DNM1 (0.43) | DNM1LSS | |
| SCHEMBL24186699 | 0.91 | DNM1 (0.56) | DNM1LSSLPAR1LPAR3LPAR2 | |
| SCHEMBL15894688 | 0.87 | DNM1 (0.50) | DNM1LSSLPAR1LPAR3LPAR2 | |
| SCHEMBL6533882 | 0.87 | DNM1 (0.60) | DNM1EPHX2 | |
| SCHEMBL6532065 | 0.87 | DNM1 (0.60) | DNM1EPHX2 | |
| SCHEMBL29723566 | 0.87 | DNM1 (0.60) | DNM1EPHX2 | |
| SCHEMBL6532072 | 0.87 | DNM1 (0.60) | DNM1EPHX2 | |
| SCHEMBL6533877 | 0.87 | DNM1 (0.60) | DNM1EPHX2 | |
| SCHEMBL19866319 | 0.86 | DNM1 (0.50) | DNM1LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070116767-A1 | Chitosan-microparticles for ifn gene delivery | UNIVERSITY OF SOUTH FLORIDA | 2007-05-24 | — | — | US | disclosed |
| US-20050266093-A1 | Nanogene therapy for cell proliferation disorders | UNIVERSITY OF SOUTH FLORIDA | 2005-12-01 | — | — | US | disclosed |
| WO-2005105136-A1 | NANOGENE THERAPY FOR CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-11-10 | — | — | WO | disclosed |
| US-5783566-A | Method for increasing or decreasing transfection efficiency | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-07-21 | — | — | US | disclosed |
| WO-1997034483-A1 | METHODS FOR INCREASING OR DECREASING TRANSFECTION EFFICIENCY | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1997-09-25 | — | — | WO | disclosed |