Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526732 | 0.95 | DNM1 (0.46) | DNM1LSSLPAR1LPAR3LPAR2 | |
| SCHEMBL21380052 | 0.93 | DNM1 (0.43) | DNM1LSS | |
| SCHEMBL24186699 | 0.89 | DNM1 (0.56) | DNM1LSSLPAR1LPAR3LPAR2 | |
| SCHEMBL15894688 | 0.86 | DNM1 (0.50) | DNM1LSSLPAR1LPAR3LPAR2 | |
| SCHEMBL20139488 | 0.85 | DNM1 (0.54) | DNM1EPHX2 | |
| SCHEMBL19866319 | 0.84 | DNM1 (0.50) | DNM1LSS | |
| SCHEMBL30284549 | 0.84 | ALDH1A1 (0.44) | — | |
| SCHEMBL19629931 | 0.83 | FAAH (0.39) | LPAR1LPAR3LPAR2EPHX2 | |
| SCHEMBL6533882 | 0.82 | DNM1 (0.60) | DNM1EPHX2 | |
| SCHEMBL6532072 | 0.82 | DNM1 (0.60) | DNM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250162978-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | UNIV RAMOT (IL) | 2025-05-22 | — | — | US | claimed |
| US-11851389-B2 | Cationic lipids for nucleic acid delivery and preparation thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-12-26 | — | — | US | claimed |
| CN-110167922-B | Cationic lipids for nucleic acid delivery and preparation thereof | 特拉维夫大学拉莫特有限公司 | 2023-09-19 | — | — | CN | claimed |
| EP-3538515-B1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | UNIV RAMOT (IL) | 2022-07-20 | — | — | EP | claimed |
| US-20190292130-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-09-26 | — | — | US | claimed |
| EP-3538515-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | Ramot at Tel-Aviv University Ltd. (IL) | 2019-09-18 | — | — | EP | claimed |
| WO-2018087753-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) | 2018-05-17 | — | — | WO | claimed |
| EP-3538515-B1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | UNIV RAMOT (IL) | 2022-07-20 | — | — | EP | disclosed |
| US-20190292130-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-09-26 | — | — | US | disclosed |
| WO-2018087753-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | TECHNOLOGY INNOVATION MOMENTUM FUND (ISRAEL) LIMITED PARTNERSHIP (IL) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11851389-B2 | Cationic lipids for nucleic acid delivery and preparation thereof | NPC1L1, NPC1, CETP | DNM1 165/4885LSS 721/4885LPAR1 30/4885 |
| US-20250162978-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | NPC1L1, NPC1, CETP | DNM1 165/4885LSS 721/4885LPAR1 30/4885 |
| US-20190292130-A1 | CATIONIC LIPIDS FOR NUCLEIC ACID DELIVERY AND PREPARATION THEREOF | NPC1L1, NPC1, CETP | DNM1 165/4885LSS 721/4885LPAR1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.