⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529389 | 0.85 | ALDH1A1 (0.32) | — | |
| SCHEMBL2390259 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL11364223 | 0.81 | ALDH1A1 (0.32) | — | |
| SCHEMBL1120013 | 0.80 | TAAR1 (0.34) | — | |
| Benzene SCHEMBL28178850 | 0.80 | TAAR1 (0.34) | — | |
| SCHEMBL5799565 | 0.79 | — | — | |
| SCHEMBL7422830 | 0.79 | — | — | |
| SCHEMBL2770558 | 0.79 | — | — | |
| SCHEMBL6607749 | 0.79 | — | — | |
| SCHEMBL7427190 | 0.79 | RARA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111748339-A | Organic electroluminescent compound and manufacturing method of device thereof | 南京高光半导体材料有限公司 | 2020-10-09 | — | — | CN | disclosed |
| US-20070254889-A1 | Compounds and methods useful for rescuing cells from beta-amyloid toxicity and treatment of Alzheimer's disease | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2007-11-01 | — | — | US | disclosed |
| US-20050271584-A1 | Biphenyls and fluorenes as imaging agents in alzheimer's disease | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2005-12-08 | — | — | US | disclosed |
| EP-1553985-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | The Trustees of The University of Pennsylvania (US) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004032975-A2 | BIPHENYLS AND FLUORENES AS IMAGING AGENTS IN ALZHEIMER'S DISEASE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2004-04-22 | — | — | WO | disclosed |