Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14990456 | 0.86 | LMNA (0.64) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL3923049 | 0.86 | LMNA (0.64) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL4299694 | 0.82 | LMNA (0.52) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL368310 | 0.81 | LMNA (0.56) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL15158309 | 0.78 | LMNA (0.59) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL1260875 | 0.78 | LMNA (0.60) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2122717 | 0.78 | LMNA (0.60) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2117527 | 0.78 | LMNA (0.60) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL2118062 | 0.78 | LMNA (0.60) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL223046 | 0.78 | LMNA (0.60) | LMNAESR1ADORA3CDC25AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11969528-B2 | Drug eluting stent and method of use of the same for enabling restoration of functional endothelial cell layers | SINO MEDICAL SCIENCES TECHNOLOGY INC. (CN) | 2024-04-30 | — | — | US | disclosed |
| US-11660214-B2 | Drug eluting stent and method of use of the same for enabling restoration of functional endothelial cell layers | SINO MEDICAL SCIENCES TECHNOLOGY INC. (CN) | 2023-05-30 | — | — | US | disclosed |
| US-20210361449-A1 | DRUG ELUTING STENT AND METHOD OF USE OF THE SAME FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS | SINO MEDICAL SCIENCES TECHNOLOGY INC. (CN) | 2021-11-25 | — | — | US | disclosed |
| US-11039942-B2 | Drug eluting stent and method of use of the same for enabling restoration of functional endothelial cell layers | SINO MEDICAL SCIENCES TECHNOLOGY INC. (CN) | 2021-06-22 | — | — | US | disclosed |
| EP-3525722-A1 | DRUG ELUTING STENT AND METHOD OF USE OF THE SAME FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS | Sino Medical Sciences Technology Inc. (CN) | 2019-08-21 | — | — | EP | disclosed |
| WO-2018113416-A1 | DRUG ELUTING STENT AND METHOD OF USE OF THE SAME FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS | SINO MEDICAL SCIENCES TECHNOLOGY INC. (CN) | 2018-06-28 | — | — | WO | disclosed |
| US-20180042738-A1 | DRUG ELUTING STENT AND METHOD OF USE OF THE SAME FOR ENABLING RESTORATION OF FUNCTIONAL ENDOTHELIAL CELL LAYERS | SINO MEDICAL SCIENCES TECHNOLOGY INC. (CN) | 2018-02-15 | — | — | US | disclosed |
| US-9884142-B2 | Drug eluting stent with a biodegradable release layer attached with an electro-grafted primer coating | ALCHIMEDICS (FR) | 2018-02-06 | — | — | US | disclosed |
| US-20140296967-A1 | DRUG ELUTING STENT WITH A BIODEGRADABLE RELEASE LAYER ATTACHED WITH AN ELECTRO-GRAFTED PRIMER COATING | ALCHIMEDICS (FR) | 2014-10-02 | — | — | US | disclosed |
| US-20070288088-A1 | Drug eluting stent with a biodegradable release layer attached with an electro-grafted primer coating | ALCHIMEDICS (FR) | 2007-12-13 | — | — | US | disclosed |