Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL875663 | 0.75 | TSHR (0.73) | TSHRHTTKMT2AMEN1CYP1A2 | |
| Chlorobenzene SCHEMBL28111876 | 0.73 | TSHR (0.69) | TSHRHTTKMT2AMEN1CYP1A2 | |
| Chlorobenzene SCHEMBL29291039 | 0.72 | — | — | |
| SCHEMBL6739890 | 0.72 | — | — | |
| Chlorobenzene SCHEMBL27462595 | 0.71 | TSHR (0.65) | TSHRCYP1A2CES2CES1ACP3 | |
| Chlorobenzene SCHEMBL31175844 | 0.71 | TSHR (0.65) | TSHRCYP1A2CES2CES1ACP3 | |
| Chlorobenzene SCHEMBL6285547 | 0.71 | TSHR (0.65) | TSHRCYP1A2CES2CES1ACP3 | |
| Chlorobenzene SCHEMBL28960547 | 0.70 | TSHR (0.55) | TSHRHTTKMT2ACES2CES1 | |
| Chlorobenzene SCHEMBL9749325 | 0.70 | TSHR (0.55) | TSHRHTTKMT2AMEN1CYP1A2 | |
| Water SCHEMBL29412656 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213365-A1 | Novel polymorphs of montelukast ammonium salts and processes for preparation therefor | CHEMAGIS LTD. (IL) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213365-A1 | Novel polymorphs of montelukast ammonium salts and processes for preparation therefor | ATP6V1A, ATP6V1H, ATP6V1G1 | TSHR 4191/4885HTT 3560/4885KMT2A 4339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.