Water

Water

SCHEMBL29412656

CN(C)P(=O)(F)N(C)C.O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118899 0.96
SCHEMBL6739890 0.96
Benzene SCHEMBL5152353 0.86 HTT (0.38)
Methylene Chloride SCHEMBL1604482 0.83 HTT (0.30)
SCHEMBL908858 0.81 CTSA (0.33)
Dimethylformamide SCHEMBL4046504 0.81 TSHR (0.53)
SCHEMBL8091799 0.78 CA2 (0.34)
Diethylamine SCHEMBL17396366 0.76 TP53 (0.42)
SCHEMBL31628393 0.75
Isobutyramide SCHEMBL9651004 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116145433-A Method for synthesizing polyurethane resin by wet method and device for synthesizing polyurethane resin 台州禾欣高分子新材料有限公司 2023-05-23 CN claimed
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS INC (US) 2026-05-21 US disclosed
CN-122037917-A Eu (Eu)3+Complex AIE sensor and preparation and fluorescence cycle recognition Cu thereof2+And the use of ATP 陇东学院 2026-05-15 CN disclosed
US-12590115-B2 Technologies useful for oligonucleotide preparation WAVE LIFE SCIENCES LTD. (SG) 2026-03-31 US disclosed
EP-3562841-B1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF HOFFMANN LA ROCHE (CH) 2026-03-25 EP disclosed
US-20260077056-A1 LINKER-PAYLOAD COMPOUND, CONJUGATES AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE SUZHOU CO LTD (CN) 2026-03-19 US disclosed
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-12570665-B2 Compositions comprising fullerenyl mesochlorin nano-photosensitizers with covalently bound antibiotics and their uses in combination therapy UNIVERSITY OF MASSACHUSETTS (US) 2026-03-10 US disclosed
US-20260055133-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR SYNTHESIS WAVE LIFE SCIENCES LTD (SG) 2026-02-26 US disclosed
US-12559573-B2 Biotin-specific monoclonal antibody and use thereof ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2026-02-24 US disclosed
CN-111393445-B Phenazine derivative-based supramolecular sensor and preparation and application thereof 西北师范大学 2022-04-15 CN disclosed
CN-111393445-B Phenazine derivative-based supramolecular sensor and preparation and application thereof 西北师范大学 2022-04-15 CN disclosed
US-20220112227-A1 CYCLIC SUPPORTED CATALYSTS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-04-14 US disclosed
US-20220106408-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS GMBH (DE) 2022-04-07 US disclosed
US-20220107310-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-04-07 US disclosed
US-20220107309-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS GMBH (DE) 2022-04-07 US disclosed
CN-109971465-B Multifunctional fluorescent probe with ESIPT (electron fluorescence tomography) and AIE (electron emission tomography) properties and preparation method and application thereof 渤海大学 2022-03-18 CN disclosed
WO-2022043238-A1 PENTAVALENT VACCINE AGAINST NEISSERIA MENINGITIDIS COMPRISING A SYNTHETIC MEN A ANTIGEN GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-03-03 WO disclosed
CN-110967325-B Column [5] arene supramolecular compound modified by mercaptoester and synthesis and application thereof 西北师范大学 2022-02-11 CN disclosed
CN-110967325-B Column [5] arene supramolecular compound modified by mercaptoester and synthesis and application thereof 西北师范大学 2022-02-11 CN disclosed