Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5527781 | 0.97 | RXFP1 (0.38) | EPHX2RXFP1ALDH1A1HPGDHTT | |
| SCHEMBL5522515 | 0.95 | CNR1 (0.37) | EPHX2RXFP1ALDH1A1HPGDHTT | |
| SCHEMBL5553132 | 0.82 | KMT2A (0.48) | EPHX2ALDH1A1HPGDHTTKMT2A | |
| SCHEMBL13494051 | 0.81 | HPGD (0.44) | EPHX2RXFP1ALDH1A1HPGDHTT | |
| SCHEMBL5528292 | 0.80 | RORC (0.35) | KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5557908 | 0.79 | KMT2A (0.45) | EPHX2ALDH1A1HPGDHTTKMT2A | |
| SCHEMBL5520030 | 0.78 | NPC1 (0.36) | ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL5528716 | 0.78 | KMT2A (0.34) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5522474 | 0.78 | SMN1; SMN2 (0.37) | ALDH1A1HPGDKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5527791 | 0.77 | SMN1; SMN2 (0.36) | ALDH1A1HPGDHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | EPHX2 2567/4885RXFP1 4640/4885ALDH1A1 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.