Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.35 |
| ▸ | RORB | Q92753 | 9/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GALR2 | O43603 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5520030 | 0.87 | NPC1 (0.36) | CNR1CNR2NPC1RAB9AL3MBTL1 | |
| SCHEMBL5520454 | 0.83 | ALDH1A1 (0.44) | NPC1RAB9AGAASMN1; SMN2MEN1 | |
| SCHEMBL5527764 | 0.80 | EPHX2 (0.40) | L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5558085 | 0.78 | ALDH1A1 (0.37) | RORCRORBNPC1RAB9AL3MBTL1 | |
| SCHEMBL5527781 | 0.77 | RXFP1 (0.38) | CNR1CNR2L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL5527718 | 0.77 | SMN1; SMN2 (0.36) | CNR1CNR2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9643564 | 0.77 | MEN1 (0.39) | CNR1CNR2NPC1RAB9AL3MBTL1 | |
| SCHEMBL5522515 | 0.76 | CNR1 (0.37) | CNR1CNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25205989 | 0.75 | MEN1 (0.35) | CNR1CNR2L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL5527584 | 0.75 | L3MBTL1 (0.45) | CNR1CNR2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108565-A1 | PYRROLE CARBOXYLIC ACID DERIVATIVES AS ANTIBACTERIAL AGENTS | POLI, POLB, POLA1 | RORC 1249/4885RORB 1052/4885CNR1 2732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.