Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5532315 | 0.76 | ALDH1A1 (0.42) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL633598 | 0.69 | NR1H2 (0.63) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL371042 | 0.68 | L3MBTL1 (0.74) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL15716944 | 0.68 | ALDH1A1 (0.50) | ADORA2AADORA3ADORA1ADORA2BMEN1 | |
| SCHEMBL3424387 | 0.67 | ADORA2A (0.90) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL11585315 | 0.67 | MEN1 (0.79) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL12176998 | 0.67 | MEN1 (0.79) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL12957698 | 0.67 | KMT2A (0.65) | ADORA2AADORA3ADORA1POLBADORA2B | |
| Hydrochloric Acid SCHEMBL15716777 | 0.67 | NR1H2 (0.59) | ADORA2AADORA3ADORA1POLBADORA2B | |
| SCHEMBL17720978 | 0.66 | L3MBTL1 (0.70) | ADORA2AADORA3ADORA1POLBADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | RIGEL PHARMACEUTICALS, INC. (US) | 2007-06-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142402-A1 | Kinase Inhibitors And Their Uses | BTK, SYK, LYN | ADORA2A 3008/4885ADORA3 3723/4885ADORA1 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.