Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336920 | 0.95 | KDM4E (0.49) | ALDH1A1KDM4ECA1MAPTPOLB | |
| SCHEMBL809416 | 0.95 | KDM4E (0.49) | ALDH1A1KDM4ECA1MAPTPOLB | |
| SCHEMBL814580 | 0.95 | KDM4E (0.49) | ALDH1A1KDM4ECA1MAPTPOLB | |
| SCHEMBL5534175 | 0.93 | KDM4E (0.48) | ALDH1A1KDM4ECA1MAPTPOLB | |
| SCHEMBL5350543 | 0.93 | KDM4E (0.48) | ALDH1A1KDM4ECA1MAPTPOLB | |
| SCHEMBL5350552 | 0.93 | KDM4E (0.48) | ALDH1A1KDM4ECA1MAPTPOLB | |
| SCHEMBL5528790 | 0.89 | ALDH1A1 (0.40) | ALDH1A1KDM4ECA1MAPTGFER | |
| SCHEMBL5534186 | 0.82 | CA1 (0.42) | ALDH1A1KDM4ECA1GFERPOLB | |
| SCHEMBL14369908 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4ECA1MAPTGFER | |
| SCHEMBL14369909 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4ECA1MAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070055081-A1 | Processes for production of alpha-aminooxyketones and alpha-hydroxyketones | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1717221-A1 | PROCESSES FOR PRODUCTION OF ALPHA-AMINOOXYKETONES AND ALPHA-HYDROXYKETONES | Japan Science and Technology Agency (JP) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055081-A1 | Processes for production of alpha-aminooxyketones and alpha-hydroxyketones | KHK, HCCS, XDH | ALDH1A1 2256/4885KDM4E 1108/4885CA1 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.