Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5528393 | 1.00 | EPHX2 (0.60) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| Phenylacetic Acid SCHEMBL27770065 | 0.85 | EPHX2 (0.59) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL3944464 | 0.85 | ALDH1A1 (0.69) | KMT2AL3MBTL1KDM1AMAOBMEN1 | |
| SCHEMBL3944460 | 0.85 | ALDH1A1 (0.69) | KMT2AL3MBTL1KDM1AMAOBMEN1 | |
| SCHEMBL4266530 | 0.85 | KMT2A (0.58) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL5694937 | 0.85 | KMT2A (0.58) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL7467219 | 0.85 | KMT2A (0.58) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL6153463 | 0.85 | ALDH1A1 (0.69) | KMT2AL3MBTL1KDM1AMAOBMEN1 | |
| SCHEMBL4266535 | 0.85 | KMT2A (0.58) | EPHX2KMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL14376044 | 0.84 | KMT2A (0.53) | EPHX2KMT2AL3MBTL1KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | ARENA PHARMACEUTICALS, INC. | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010671-A1 | Novel quinazoline derivatives and methods of treatment related to the use thereof | MCHR1, GPR119, MCHR2 | EPHX2 3017/4885KMT2A 792/4885L3MBTL1 3309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.