Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | OXTR | P30559 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525755 | 0.90 | ALDH1A1 (0.37) | TSPOOXTRALDH1A1TSHRAVPR1A | |
| SCHEMBL5529681 | 0.87 | MALT1 (0.38) | TSPOOXTRALDH1A1TSHRAVPR1A | |
| SCHEMBL5530217 | 0.86 | ALDH1A1 (0.35) | TSPOOXTRALDH1A1TSHRAVPR1A | |
| SCHEMBL5528138 | 0.85 | ALDH1A1 (0.35) | TSPOOXTRALDH1A1TSHRAVPR1A | |
| SCHEMBL5525424 | 0.84 | TDP1 (0.38) | OXTRALDH1A1TSHRAVPR1AALOX5 | |
| SCHEMBL5525761 | 0.84 | OXTR (0.42) | OXTRALDH1A1TSHRAVPR1A | |
| SCHEMBL5529157 | 0.83 | ALDH1A1 (0.34) | TSPOOXTRALDH1A1TSHRAVPR1A | |
| SCHEMBL5265509 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TSHRALOX5 | |
| SCHEMBL5527560 | 0.81 | ALDH1A1 (0.35) | OXTRALDH1A1TSHRAVPR1AALOX5 | |
| SCHEMBL5267019 | 0.80 | CA9 (0.42) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| US-20070219210-A1 | Amidopyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1698626-A1 | AMIDOPYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-09-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219210-A1 | Amidopyrazole Derivative | PTGER1, PTGS1, PTGER2 | TSPO 2452/4885OXTR 1114/4885ALDH1A1 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.