Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | RORB | Q92753 | 2/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6953541 | 0.86 | RECQL (0.60) | RECQLMAPTNOS2NPC1ALDH1A1 | |
| SCHEMBL6957797 | 0.84 | PTGER1 (0.58) | RECQLKDM4ENPC1KMT2APTGER1 | |
| SCHEMBL2705425 | 0.81 | RECQL (0.65) | RECQLMAPTRORCRORBKDM4E | |
| SCHEMBL12165498 | 0.79 | RECQL (0.61) | RECQLMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL9540049 | 0.78 | RECQL (0.79) | RECQLNOS2FADS1KDM4ENPC1 | |
| SCHEMBL12165534 | 0.78 | RECQL (0.60) | RECQLMAPTNOS2RORCRORB | |
| SCHEMBL12165545 | 0.76 | RECQL (0.48) | RECQLMAPTNOS2FADS1NPC1 | |
| SCHEMBL1809103 | 0.76 | MRGPRX1 (0.49) | RECQLMAPTNOS2FADS1NPC1 | |
| SCHEMBL29515875 | 0.76 | RECQL (0.71) | RECQLMAPTNOS2FADS1KDM4E | |
| SCHEMBL333224 | 0.76 | RECQL (0.71) | RECQLMAPTNOS2FADS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2719698-A1 | Methods for preparing aurora kinase inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-04-16 | — | — | EP | disclosed |
| US-20070185087-A1 | Compounds and methods for inhibiting mitotic progression | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185087-A1 | Compounds and methods for inhibiting mitotic progression | AURKC, AURKA, AURKB | RECQL 414/4885MAPT 676/4885NOS2 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.