SCHEMBL5528958

SCHEMBL5528958

CCc1nc(Nc2cccc(S(=O)(=O)O)c2)nc(N(C)C)n1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDH2 P48735 1/20 0.45
ALDH1A1 P00352 2/20 0.45
CA1 P00915 6/20 0.44
CA2 P00918 6/20 0.44
CA9 Q16790 6/20 0.44
CA12 O43570 4/20 0.42
PDE4B Q07343 6/20 0.41
PDE4D Q08499 3/20 0.41
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.39
PDE5A O76074 1/20 0.39
SNCA P37840 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033143 0.89 IDH2 (0.42) IDH2ALDH1A1CA1CA2CA9
SCHEMBL17033144 0.87 IDH2 (0.41) IDH2ALDH1A1CA1CA2CA9
SCHEMBL16213857 0.84 PDE4B (0.43) PDE4BPDE4DPDE5ASNCA
SCHEMBL16213862 0.84 SNCA (0.50) CA1CA2CA9CA12PDE4B
SCHEMBL15984414 0.84 CA1 (0.49) IDH2ALDH1A1CA1CA2CA9
SCHEMBL16213850 0.83 NPC1 (0.51) ALDH1A1PDE4BPDE4DPOLBKMT2A
SCHEMBL15984404 0.82 KCNH3 (0.51) IDH2ALDH1A1CA1CA2CA9
SCHEMBL15804174 0.81 PTK2 (0.48) IDH2ALDH1A1CA1CA2CA9
SCHEMBL15804163 0.81 CA1 (0.49) IDH2ALDH1A1CA1CA2CA9
SCHEMBL14401754 0.81 CA1 (0.41) ALDH1A1CA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8876915-B2 Coloring composition and ink for inkjet recording FUJIFILM CORPORATION (JP) 2014-11-04 US disclosed
US-20120121868-A1 Phthalocyanines and Their Use in Ink-Jet Printing FUJIFILM IMAGING COLORANTS LIMITED (GB) 2012-05-17 US disclosed