Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.38 |
| ▸ | TNK1 | Q13470 | 5/20 | 0.38 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5525690 | 0.87 | PARP1 (0.40) | PARP1TNK1TNK2TP53ADRA1A | |
| SCHEMBL5525019 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5529068 | 0.85 | TP53 (0.37) | TP53ADRA1AADRA1BDRD2HTR1A | |
| SCHEMBL5522872 | 0.84 | MAPT (0.43) | ADRA1BDRD2HTR1ADRD4DRD3 | |
| SCHEMBL5530513 | 0.84 | MAPT (0.43) | PARP1TNK1TNK2ADRA1AADRA1B | |
| SCHEMBL5528190 | 0.82 | STAT3 (0.43) | TP53ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5535139 | 0.81 | NPC1 (0.37) | PARP1HTR1ADRD4ALDH1A1HTT | |
| SCHEMBL5531534 | 0.80 | PARP1 (0.43) | PARP1TNK1TNK2HTR1AKDM4E | |
| SCHEMBL5527455 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5524887 | 0.76 | PARP1 (0.41) | PARP1TNK1TNK2DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | TP53, RB1, HRAS | PARP1 435/4885TNK1 2730/4885TNK2 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.