Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.37 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5530837 | 0.88 | MTOR (0.39) | MTORRPTORMLST8HTR7HTR1A | |
| SCHEMBL5530846 | 0.88 | DRD2 (0.39) | TP53DPP4HTR1ADRD2DRD4 | |
| SCHEMBL5528886 | 0.86 | ALDH1A1 (0.49) | MTORRPTORMLST8HTR7KMT2A | |
| SCHEMBL5525288 | 0.85 | KMT2A (0.45) | TP53DRD2DRD4DRD3KMT2A | |
| SCHEMBL5525433 | 0.85 | SMN1; SMN2 (0.42) | DRD2DRD4DRD3KMT2AKDM4E | |
| SCHEMBL5529004 | 0.85 | PARP1 (0.38) | TP53HTR7HTR1AADRA1AADRA1B | |
| SCHEMBL5529697 | 0.77 | DRD2 (0.38) | MTORRPTORMLST8HTR7HTR1A | |
| SCHEMBL5527455 | 0.77 | ALDH1A1 (0.47) | KMT2AKDM4E | |
| SCHEMBL5529630 | 0.75 | ALDH1A1 (0.42) | MTORRPTORMLST8DRD2KDM4E | |
| SCHEMBL5525690 | 0.75 | PARP1 (0.40) | TP53ADRA1AADRA1BDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-09-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213339-A1 | Quinolone Carboxylic Acid Derivatives for Treatment of Hyperproliferative Conditions | TP53, RB1, HRAS | TP53 1/4885MTOR 731/4885RPTOR 1677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.