Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | AMD1 | P17707 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5529325 | 1.00 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL14390216 | 1.00 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL7189813 | 1.00 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL6576927 | 0.82 | TYMP (0.52) | PDE4APDE4BPDE4CPDE4DTYMP | |
| SCHEMBL6229115 | 0.82 | ADORA3 (0.54) | PI4KAPI4K2BPI4K2API4KBPRMT5 | |
| SCHEMBL6253348 | 0.82 | ADORA3 (0.54) | PI4KAPI4K2BPI4K2API4KBPRMT5 | |
| SCHEMBL5534004 | 0.82 | ADORA3 (0.54) | PI4KAPI4K2BPI4K2API4KBPRMT5 | |
| SCHEMBL6229111 | 0.82 | ADORA3 (0.54) | PI4KAPI4K2BPI4K2API4KBPRMT5 | |
| SCHEMBL6796631 | 0.79 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL6572952 | 0.79 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297787-B2 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | GLAXO GROUP LIMITED (GB) | 2007-11-20 | — | — | US | disclosed |
| EP-1370569-B1 | PROCESS FOR PREPARING N6-SUBSTITUTED AMINOPURINE RIBOFURANOSE NUCLEOSIDES | GLAXO GROUP LTD (GB) | 2005-08-31 | — | — | EP | disclosed |
| US-20050176949-A1 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | GLAXO GROUP LIMITED (GB) | 2005-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176949-A1 | Process for preparing N6 substituted aminopurine ribofuranose nucleosides | ADORA3, NUDT1, ADORA1 | PI4KA 2558/4885PI4K2B 3589/4885PI4K2A 3135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.